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resorcinol/sulfur (Acnotex, Clearasil Stay Clear Acne Treatment Cream, Clearasil Adult Tinted Acne Treatment Cream, Rezamid, Glytone Flesh Tinted Acne Treatment Lotion, Pernox Scrub for Oily Skin)

 

Classes: Acne Agents, Topical

Dosing and uses of Acnomel, Acnotex (resorcinol/sulfur)

 

Adult dosage forms and strengths

resorcinol/sulfur

topicaL

  • 2%/4%
  • 2%/5%
  • 2%/8%

 

Acne Vulgaris

After cleansing, apply sparingly to affected area(s) up to TId

Product content varies, check individual labeling

 

Pediatric dosage forms and strengths

resorcinol/sulfur

topicaL

  • 2%/4%
  • 2%/5%
  • 2%/8%

 

Acne Vulgaris

Adolescents: As adults; after cleansing, apply sparingly to affected area(s) up to TId

Product content varies, check individual labeling

 

Acnomel, Acnotex (resorcinol/sulfur) adverse (side) effects

Frequency not defined

Erythema

Excessive desquamation

Skin irritation/inflammation

 

Warnings

Contraindications

Hypersensitivity

Existing skin rash or irritation

 

Cautions

External use only

Discontinue if excessive skin irritation develops

 

Pregnancy and lactation

Pregnancy category: C

Lactation: insufficient data; drug absorbed through intact & broken skin

Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

 

Pregnancy categories

A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA: Information not available.

 

Pharmacology of Acnomel, Acnotex (resorcinol/sulfur)

Mechanism of action

Resorcinol and sulfur are keratolytic agents