Siberian Ginseng (Acanthopanax Senticosus, Devil's Bush, Eleuthero, eleutherococcus, Eleutherococcus Senticosus, Shigoka, Thorny Pepperbrush, Touch Me Not, Untouchable, Wild Pepper)
Classes: Adaptogens, Herbals
- Suggested dosing of Acanthopanax Senticosus, Devil's Bush (Siberian ginseng)
- Suggested uses of Acanthopanax Senticosus, Devil's Bush (Siberian ginseng)
- Acanthopanax Senticosus, Devil's Bush (Siberian ginseng) adverse (side) effects
- Warnings
- Pregnancy
- Pharmacology of Acanthopanax Senticosus, Devil's Bush (Siberian ginseng)
Suggested dosing of Acanthopanax Senticosus, Devil's Bush (Siberian ginseng)
0.6-3 g dried root PO qDay
400 mg standardized extract PO qDay/TId
Therapy for 30-60 days, followed by 2-3 weeks off
Extract standardized to 0.3% eleutheroside e
Suggested uses of Acanthopanax Senticosus, Devil's Bush (Siberian ginseng)
Adaptogen: adapt to internal/external stressors, fight fatigue, increase stamina
Reduce severity/duration of herpes simplex type II infections
Arterosclerosis, athletic/work performance enhancement, chronic fatigue syndrome, craniocerebral trauma, diabetes, fibromyalgia, hypertension/hypotension, immunostimulant, neuroses
Efficacy
Possibly effective for common cold and herpes simplex virus type 2
Possibly ineffective for athletic performance
Insufficient reliable evidence on chronic fatigue syndrome, cognitive performance, heart disease, influenza, ischemic stroke and quality of life
Acanthopanax Senticosus, Devil's Bush (Siberian ginseng) adverse (side) effects
Frequency not defined
Anxiety
Drowsiness
Headache
Hypertension
Hypoglycemia
Insomnia
Irritability
Mastalgia
Muscle spasms
Nerve inflammation
Palpitations
Pericardial pain
Tachycardia
Warnings
Contraindications
Breast cancer, endometrial cancer, endometriosis, febrile conditions, hormone sensitive conditions, hypertension, ovarian cancer, uterine fibroids
Cautions
CAD, cardiovascular disorders, mania, MI, psychiatric disorders, rheumatic heart disease, schizophrenia
Pregnancy and lactation
Pregnancy category: N/A
Lactation: N/A
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Acanthopanax Senticosus, Devil's Bush (Siberian ginseng)
Mechanism of action
Eleuthorosides A through M modulate pituitary-adrenocortical axis
Antioxidant and immunostimulant activity