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Anafranil vs. Prozac

Are Anafranil and Prozac the Same Thing?

Anafranil (clomipramine hydrochloride) and Prozac (fluoxetine) are types of antidepressants used to treat symptoms of obsessive-compulsive disorder (OCD).

Prozac is also used to treat depression, bulimia, panic disorder, and premenstrual dysphoric disorder (PMDD).

Anafranil and Prozac are different types of antidepressants. Anafranil is a tricyclic and Prozac is a selective serotonin reuptake inhibitor (SSRI).

What Are Possible Side Effects of Anafranil?

Common side effects of Anafranil include:

Tell your doctor if you have unlikely but serious side effects of Anafranil including:

  • mental/mood changes (e.g., confusion, depression),
  • enlarged or painful breasts,
  • unwanted breast milk production,
  • irregular or painful menstrual periods,
  • muscle stiffness,
  • ringing in the ears,
  • shakiness (tremors), or
  • trouble urinating.

What Are Possible Side Effects of Prozac?

Common side effects of Prozac include:

  • nausea,
  • upset stomach,
  • constipation,
  • headaches,
  • anxiety,
  • sleep problems (insomnia),
  • drowsiness,
  • dizziness,
  • nervousness,
  • heart palpitations,
  • loss of appetite or increase in appetite,
  • weight changes,
  • cold symptoms (stuffy nose, sneezing, sore throat),
  • dry mouth,
  • decreased sex drive,
  • impotence, or
  • difficulty having an orgasm.

What Is Anafranil?

Anafranil (clomipramine hydrochloride) is a tricyclic antidepressant used to treat symptoms of obsessive-compulsive disorder (OCD) such as recurrent thoughts or feelings and repetitive actions.

What Is Prozac?

Prozac is a prescription medicine used to treat depression. It is important to talk with your healthcare provider about the risks of treating depression and also the risks of nottreating it. You should discuss all treatment choices with your healthcare provider.

Prozac is used to treat:

  • Major Depressive Disorder (MDD)
  • Obsessive Compulsive Disorder (OCD)
  • Bulimia Nervosa*
  • Panic Disorder*
  • Depressive episodes associated with Bipolar I Disorder, taken with olanzapine (Zyprexa)
  • Treatment Resistant Depression (depression that has not gotten better with atleast 2 other treatments), taken with olanzapine (Zyprexa)*

*Not approved for use in children

Talk to your healthcare provider if you do not think that your condition is getting betterwith Prozac treatment.

What Drugs Interact With Anafranil?

Anafranil may interact with SSRI antidepressants, cimetidine, guanethidine, methylphenidate, phenytoin, warfarin, heart or blood pressure medications, heart rhythm medications, or anti-psychotic medications. Many other drugs can interact with Anafranil.

What Drugs Interact With Prozac?

Prozac may interact with cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, medicine for seizures or anxiety, monoamine oxidase inhibitors (MAOIs), nonsteroidal anti-inflammatory drugs (NSAIDs), other antidepressants, blood thinners, or migraine headache medicines.

Prozac may also interact with alprazolam, clopidogrel, clozapine, flecainide, haloperidol, nebivolol, vinblastine, or seizure medications.

Withdrawal symptoms may occur if you suddenly stop taking Prozac.

How Should Anafranil Be Taken?

The adult starting dose of Anafranil is 25 mg daily and gradually increased, as tolerated, to approximately 100 mg during the first 2 weeks. Maximum dose is 250 mg daily. Consult your doctor for pediatric or adolescent dosing.

How Should Prozac Be Taken?

Take Prozac exactly as prescribed. Your healthcare provider may need to change the dose of Prozac until it is the right dose for you.

Prozac may be taken with or without food.

If you miss a dose of Prozac, take the missed dose as soon as you remember.If it is almost time for the next dose, skip the missed dose and take your nextdose at the regular time. Do not take two doses of Prozac at the same time.

If you take too much Prozac, call your healthcare provider or poison controlcenter right away, or get emergency treatment.

Disclaimer

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