Protonix vs. Dexilant

• Are Protonix and Dexilant the Same Thing?
• What Are Possible Side Effects of Protonix?
• What Are Possible Side Effects of Dexilant?
• What is Protonix?
• What is Dexilant?
• What drugs interact with Protonix?
• What drugs interact with Dexilant?
• How Should Protonix Be Taken?
• How Should Dexilant Be Taken?

Protonix (pantoprazole sodium) and Dexilant (dexlansoprazole) are proton pump inhibitors (PPIs) used to treat gastroesophageal reflux disease (GERD) and erosive esophagitis.

Side effects of Protonix include:

• injection site reactions (redness, pain, swelling),
• headache,
• nausea,
• vomiting,
• abdominal or stomach pain,
• diarrhea,
• gas,
• dizziness,
• joint pain,
• weight changes,
• drowsiness,
• tired feeling, or
• sleep problems (insomnia).

Common side effects of Dexilant include:

• diarrhea,
• nausea,
• vomiting,
• stomach pain,
• gas,
• stuffy nose,
• sneezing, or
• other cold symptoms

What is Protonix?

Protonix IV (pantoprazole sodium) is a proton pump inhibitor (PPI) used for short-term treatment (less than 10 days) of gastroesophageal reflux disease (GERD) and a history of erosive esophagitis in adult patients.

What is Dexilant?

Dexilant (dexlansoprazole) is a proton pump inhibitor (PPI) used to treat certain stomach and esophagus problems (such as acid reflux). It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough.

Protonix may interact with atazanavir, blood thinners, digoxin, diuretics (water pills), ketoconazole, or methotrexate.

Protonix may also interact with nelfinavir, ampicillin, or iron.

Dexilant may interact with atazanavir, ampicillin, digoxin, iron, blood thinners such as warfarin, or ketoconazole.

Dexilant may also interact with digoxin, tacrolimus, or clopidogrel.

The recommended adult dose of Protonix is 40 mg once daily.

• Protonix Oral Suspension should be taken 30 minutes before a meal
• Protonix Oral Suspension should only be taken with applesauce or apple juice 30 minutes before a meal.
• Protonix Oral Suspension should not be taken in or with water or other liquids, or with other foods.
• Protonix Oral Suspension should not be chewed or crushed.
• Protonix Oral Suspension packet should not be divided to make a smaller dose.

The recommended dosage of Dexilant is 30 mg once daily for up to 6 months for maintenance of healed EE, and 30 mg once daily for 4 weeks to treat symptomatic non-erosive GERD.