Buprenex vs. Oxycodone

• Are Buprenex and Oxycodone the Same Thing?
• What Are Possible Side Effects of Buprenex?
• What Are Possible Side Effects of Oxycodone?
• What Is Buprenex?
• What Is Oxycodone?
• What Drugs Interact with Buprenex?
• What Drugs Interact with Oxycodone?
• How Should Buprenex Be Taken?
• How Should Oxycodone Be Taken?

Buprenex (buprenorphine hydrochloride) and oxycodone are narcotics indicated for the relief of moderate to severe pain.

Brand names for oxycodone include Oxycontin, Roxicodone, and Xtampza ER.

Common side effects of Buprenex include:

• nausea,
• dizziness,
• spinning sensation (vertigo),
• weakness,
• tired feeling,
• sweating,
• numbness or tingly feeling,
• headache,
• depression,
• low blood pressure (hypotension),
• nausea,
• vomiting,
• constipation,
• blurred vision,
• double vision, and
• shallow breathing.

Tell your doctor if you have serious side effects of Buprenex including:

• weak or shallow breathing,
• lightheadedness,
• fainting,
• blue lips or fingernails,
• confusion,
• feelings of extreme happiness,
• fast or slow heart rate, or
• urinating less than usual or not at all.

Common side effects of Oxycodone include:

• constipation,
• nausea,
• stomach pain,
• loss of appetite,
• vomiting,
• sleepiness,
• tiredness,
• drowsiness,
• dizziness,
• lightheadedness,
• weakness,
• itching,
• headache,
• dry mouth,
• sweating, and
• decreases in the ability to feel pain.

Tell your doctor if you experience serious side effects of Oxycodone including

• respiratory depression,
• apnea (stopped breathing),
• respiratory arrest,
• circulatory depression,
• hypotension (low blood pressure),
• shock, and
• death.

Buprenex (buprenorphine hydrochloride) injectable is a narcotic drug indicated for the relief of moderate to severe pain.

Oxycontin (oxycodone hydrochloride) is an opioid drug used for the management of moderate to severe pain, usually for an extended time period. Oxycontin is not an "as needed for pain (PRN) drug." Oxycontin is available as a generic drug.

Buprenex may interact with alcohol, other narcotic pain medications, sedatives, tranquilizers, sleeping pills, muscle relaxers, other medicines that can make you sleepy or slow your breathing, dexamethasone, imatinib, isoniazid, nefazodone, St. John's wort, antibiotics, antifungal medications, barbiturates, blood thinners, heart or blood pressure medications, HIV/AIDS medicines, MAO inhibitors, medicines to treat narcolepsy, phenothiazines, or seizure medications. Tell your doctor all medications and supplements you use.

Oxycodone may interact with alcohol, other narcotic pain medications, sedatives, tranquilizers, sleeping pills, muscle relaxers, other medicines that can make you sleepy or slow your breathing, monoamine oxidase inhibitors (MAOIs), antidepressants, methscopolamine, scopolamine, bladder or urinary medications, or irritable bowel medications.

Oxycodone may also interact with mixed agonist/antagonist analgesics, macrolide antibiotics, azole-antifungals, protease inhibitors, rifampin, and cardiovascular drugs (including amiodarone and quinidine).

The usual dosage for persons 13 years of age and over is 1 ml Buprenex given by deep intramuscular or slow (over at least 2 minutes) intravenous injection at up to 6-hour intervals, as needed.

Oxycodone hydrochloride is available as controlled-release tablets in strengths of 10, 15, 20, 30, 40, 60, 80, and 160 mg tablets (60 mg and above used only for opioid tolerant patients). The tablets must be swallowed whole because broken or chewed tablets release the drug too rapidly and because Oxycodone is rapidly adsorbed, too concentrated levels will be present in the body which can lead to death. Oxycodone may interact with other narcotic pain medications, sedatives, tranquilizers, sleeping pills, muscle relaxers, other medicines that can make you sleepy or slow your breathing, pentazocine, nalbuphine, butorphanol, or buprenorphine. Tell your doctor all medications and supplements you use. This opioid is often the drug of choice for addictive use and can easily lead to dependency. Some patients may develop tolerance for Oxycodone and need to be slowly weaned off the drug. Safety has not been established in children under age 18; caution or avoidance is suggested in pregnant and breastfeeding women as infants can be born with opioid tolerance and depressed respirations. In addition, low concentrations of Oxycodone have been found in breast milk.