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Medrol vs. Solu-Medrol: Comparison
Medically reviewed by Min Clinic Staff | Updated: January 2026
- Are Solu-Medrol and Medrol the Same Thing?
- What Are Possible Side Effects of Medrol?
- What Are Possible Side Effects of Solu-Medrol?
- What Is Medrol?
- What Is Solu-Medrol?
- What Drugs Interact with Medrol?
- What Drugs Interact with Solu-Medrol?
- How Should Medrol Be Taken?
- How Should Solu-Medrol Be Taken?
Are Medrol and Solu-Medrol the Same Thing?
Medrol (methylprednisolone) and Solu-Medrol (methylprednisolone) are corticosteroids indicated to treat or manage many conditions, including endocrine disorders, rheumatic disorders, collagen diseases, dermatologic diseases, allergies, eye diseases, respiratory diseases, blood disorders, cancers, edematous states, gastrointestinal diseases, and others.
A difference is Medrol is given in tablet form while Solu-Medrol is administered by slow injection into a vein or directly into a muscle.
What Are Possible Side Effects of Medrol?
Common side effects of Medrol include:
- skin problems (acne, dry and thinning skin, easy bruising or discoloration),
- slow wound healing,
- changes in the shape or location of body fat (especially in the neck, face, arms, legs, breasts, and waist),
- nausea,
- stomach pain,
- bloating,
- headache,
- dizziness,
- spinning sensation,
- sleep problems (insomnia),
- increased sweating, and
- mood changes.
Serious side effects of Medrol include emergency medical conditions such as: