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Vemlidy vs. Viread

Are Vemlidy and Viread the Same Thing?

Vemlidy (tenofovir alafenamide) and Viread (tenofovir disoproxil fumarate) are antiviral medications used to treat chronic hepatitis B virus (HBV).

Vemlidy is used in adults with compensated liver disease.

Viread is also used in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 12 years of age and older.

Side effects of Vemlidy and Viread that are similar include headache, stomach/abdominal pain, and nausea.

Side effects of Vemlidy that are different from Viread include fatigue, cough, and back pain.

Side effects of Viread that are different from Vemlidy include iarrhea, depression, dizziness, weakness, trouble sleeping, itching or rash, and changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

Both Vemlidy and Viread may interact with antiviral medicines.

Vemlidy may also interact with drugs that induce P-gp activity, aminoglycosides, high-dose or multiple nonsteroidal anti-inflammatories (NSAIDs), anticonvulsants, antimycobacterials, and St. John's wort.

Viread may also interact with other HIV or AIDS medications, lithium, methotrexate, pain or arthritis medicines, medicines used to treat ulcerative colitis, medicines used to prevent organ transplant rejection, IV antibiotics, or injectable medications to treat osteoporosis or Paget's disease of the bones.

What Are Possible Side Effects of Vemlidy?

Common side effects of Vemlidy include:

  • headache,
  • abdominal pain,
  • fatigue,
  • cough,
  • nausea, and
  • back pain.

What Are Possible Side Effects of Viread?

Common side effects of Viread include:

  • nausea,
  • stomach pain,
  • diarrhea,
  • depression,
  • headache,
  • dizziness,
  • weakness,
  • trouble sleeping,
  • itching or rash, or
  • changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

Tell your doctor if you have unlikely but serious side effects of Viread including:

  • mental/mood changes (such as depression, anxiety, confusion).

Tell your doctor if you have rare but serious side effects of Viread including:

  • signs of kidney problems (such as a change in the amount of urine), or
  • unusual thirst.

What Is Vemlidy?

Vemlidy (tenofovir alafenamide) is a hepatitis B virus (HBV) nucleoside analog reverse transcriptase inhibitor and is indicated for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease.

What Is Viread?

Viread (tenofovir disoproxil fumarate) is an antiretroviral drug that is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 12 years of age and older. Viread is also used to treat chronic hepatitis B.

What Drugs Interact With Vemlidy?

Vemlidy may interact with drugs that induce P-gp activity, antivirals, aminoglycosides, high-dose or multiple nonsteroidal anti-inflammatories (NSAIDs), anticonvulsants, antimycobacterials, and St. John's wort. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Vemlidy. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to during pregnancy. It is unknown if Vemlidy passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Viread?

Viread may interact with other HIV or AIDS medications, lithium, methotrexate, pain or arthritis medicines, medicines used to treat ulcerative colitis, medicines used to prevent organ transplant rejection, IV antibiotics, antiviral medicines, or injectable medications to treat osteoporosis or Paget's disease of the bones. Tell your doctor all medications and supplements you use. This medication is not expected to be harmful to an unborn baby, but HIV can be passed to the baby if the mother is not properly treated during pregnancy. You should not breastfeed while you are using Viread. Women with HIV or AIDS should not breastfeed at all.

How Should Vemlidy Be Taken?

The recommended dosage of Vemlidy is 25 mg (one tablet) taken orally once daily with food.

How Should Viread Be Taken?

The dose is one 300 mg Viread Tablet once daily taken orally, without regard to food.

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