Mydayis vs. Adzenys ER

Mydayis (mixed salts of a single-entity amphetamine product) and Adzenys ER (amphetamine extended-release oral suspension) are central nervous system (CNS) stimulants used to treat attention deficit hyperactivity disorder (ADHD).

Side effects of Mydayis and Adzenys ER that are similar include insomnia, decreased appetite, weight loss, nausea, dry mouth, increased heart rate, and diarrhea.

Side effects of Mydayis that are different from Adzenys ER include irritability, anxiety, feeling jittery, tooth grinding, depression, palpitations, menstrual pain or cramping, and erectile dysfunction.

Side effects of Adzenys ER that are different from Mydayis include abdominal pain, mood changes, vomiting, nervousness, fever, nervousness, headache, agitation, dizziness, weakness or lack of energy, and urinary tract infections (UTIs).

Both Mydayis and Adzenys ER may interact with monoamine oxidase inhibitors (MAOIs), triptans, antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, St. John's wort, quinidine, ritonavir, omeprazole, esomeprazole, pantoprazole, and cimetidine.

Mydayis may also interact with acidifying or alkalinizing agents (GI and urinary).

Adzenys ER may also interact with sodium bicarbonate, acetazolamide, and some thiazides.

Withdrawal symptoms may occur if you suddenly stop taking Mydayis or Adzenys ER.

Common side effects of Mydayis include:

• insomnia,
• decreased appetite,
• decreased weight,
• irritability,
• nausea,
• dry mouth,
• increased heart rate,
• anxiety,
• feeling jittery,
• tooth grinding,
• depression,
• diarrhea,
• palpitations,
• menstrual pain or cramping, and
• erectile dysfunciton.

Central nervous system stimulants, including Mydayis, have a high potential for abuse and dependence.</

Common side effects of Adzenys ER include:

• loss of appetite,
• insomnia,
• abdominal pain,
• mood changes,
• vomiting,
• nervousness,
• nausea,
• fever,
• weight loss,
• and nervousness.

Common side effects of Adzenys ER for adult patients also include:

• dry mouth,
• headache,
• agitation,
• dizziness,
• fast heart rate,
• diarrhea,
• weakness or lack of energy,
• and urinary tract infections (UTIs).

Mydayis (mixed salts of a single-entity amphetamine product) extended-release capsules are a central nervous system (CNS) stimulant indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients 13 years and older.

Adzenys ER (amphetamine) extended-release oral suspension is a central nervous system (CNS) stimulant indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients 6 years and older.

Mydayis may interact with acidifying or alkalinizing agents (GI and urinary), monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), triptans, antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, St. John's wort, quinidine, ritonavir, omeprazole, esomeprazole, pantoprazole, and cimetidine. Tell your doctor all medications and supplements you use.

Adzenys ER may interact with monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRI), serotonin norepinephrine reuptake inhibitors (SNRI), triptans, antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, St. John's wort, sodium bicarbonate, acetazolamide, some thiazides, quinidine, ritonavir, omeprazole, esomeprazole, pantoprazole, and cimetidine. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Adzenys ER; it may harm a fetus. Adzenys ER passes into breast milk. Large dosages of amphetamines such as Adzenys ER might interfere with milk production. Because of the potential for serious adverse reactions in nursing infants, breastfeeding is not recommended during treatment with Adzenys ER. Withdrawal symptoms may occur if you suddenly stop taking Adzenys ER.

The recommended starting dose of Mydayis for adults and children 13 to 17 years is 12.5 mg.

The starting dose of Adzenys ER for pediatric patients (ages 6 to 17 years) is 6.3 mg (5 mL) once daily in the morning. Maximum dose is 18.8 mg (15 mL) for patients 6 to 12 years, and 12.5 mg (10 mL) once daily for patients 13 to 17 years. The dose of Adzenys ER for adults is 12.5 mg (10 mL) once daily in the morning.