Monovisc vs. Synvisc

• Are Synvisc and Monovisc the Same Thing?
• What Are Possible Side Effects of Monovisc?
• What Are Possible Side Effects of Synvisc?
• What is Monovisc?
• What is Synvisc?
• What Drugs Interact with Monovisc?
• What Drugs Interact with Synvisc?
• How Should Monovisc Be Taken?
• How Should Synvisc Be Taken?

Monovisc (high molecular weight hyaluronan injection) and Synvisc (hylan G-F 20) are viscosupplements used to treat pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy or simple analgesics.

Common side effects of Monovisc include:

• joint pain and swelling,
• injection site reactions,
• rash,
• headache,
• dizziness,
• chills,
• hives,
• itching,
• nausea,
• muscle cramps,
• swelling of legs and feet, and
• a general feeling of being unwell (malaise)

Common side effects of Synvisc include:

• injection site reactions (pain, swelling, warmth, stiffness, puffiness, or fluid buildup in or around the knee),
• muscle pain,
• trouble walking,
• fever,
• chills,
• nausea,
• numbness or tingly feeling,
• headache,
• dizziness,
• tired feeling, or
• itching or skin irritation around the knee.

Tell your doctor if you have serious side effects of Synvisc including:

• back pain,
• severe headache, or
• fast or pounding heartbeat.

Monovisc (high molecular weight hyaluronan injection) is a complex sugar used to treat pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy or simple analgesics (e.g., acetaminophen).

Synvisc (hylan G-F 20) is a type of osteoarthritis knee pain treatment called a viscosupplement or hyaluronan injection prescribed for treatment of osteoarthritis of the knee in patients who have failed to respond to simple analgesics.

Monovisc may interact with other drugs.

Synvisc may interact with other drugs.

Monovisc is supplied in a single-use 5 mL syringe containing a 4 mL dose of treatment.

Synvisc is administered in 3 injections in a doctor's office, done one week apart to provide relief of osteoarthritis knee pain for up to 6 months.