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Monovisc vs. Synvisc

Are Monovisc and Synvisc the Same Thing?

Monovisc (high molecular weight hyaluronan injection) and Synvisc (hylan G-F 20) are viscosupplements used to treat pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy or simple analgesics.

What Are Possible Side Effects of Monovisc?

Common side effects of Monovisc include:

What Are Possible Side Effects of Synvisc?

Common side effects of Synvisc include:

  • injection site reactions (pain, swelling, warmth, stiffness, puffiness, or fluid buildup in or around the knee),
  • muscle pain,
  • trouble walking,
  • fever,
  • chills,
  • nausea,
  • numbness or tingly feeling,
  • headache,
  • dizziness,
  • tired feeling, or
  • itching or skin irritation around the knee.

Tell your doctor if you have serious side effects of Synvisc including:

  • back pain,
  • severe headache, or
  • fast or pounding heartbeat.

What is Monovisc?

Monovisc (high molecular weight hyaluronan injection) is a complex sugar used to treat pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy or simple analgesics (e.g., acetaminophen).

What is Synvisc?

Synvisc (hylan G-F 20) is a type of osteoarthritis knee pain treatment called a viscosupplement or hyaluronan injection prescribed for treatment of osteoarthritis of the knee in patients who have failed to respond to simple analgesics.

What Drugs Interact With Monovisc?

Monovisc may interact with other drugs.

What Drugs Interact With Synvisc?

Synvisc may interact with other drugs.

How Should Monovisc Be Taken?

Monovisc is supplied in a single-use 5 mL syringe containing a 4 mL dose of treatment.

How Should Synvisc Be Taken?

Synvisc is administered in 3 injections in a doctor's office, done one week apart to provide relief of osteoarthritis knee pain for up to 6 months.

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