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Lialda vs. Delzicol

Are Delzicol and Lialda the Same Thing?

Lialda (mesalamine) and Delzicol (mesalamine) are aminosalicylate anti-inflammatory agents used to treat ulcerative colitis, and also to prevent the symptoms of ulcerative colitis from recurring.

Lialda is also used to treat proctitis and proctosigmoiditis.

Side effects of Lialda and Delzicol that are similar include vomiting, diarrhea, gas, fever, flu-like symptoms, constipation, headache, dizziness, or skin rash.

Side effects of Lialda that are different from Delzicol include nausea, stomach cramps, sore throat, or tired feeling.

Side effects of Delzicol that are different from Lialda include abdominal pain, belching, back pain, upset stomach, indigestion, nasal inflammation, runny or stuffy nose, cough, fatigue, joint pain and swelling (arthritis), gastrointestinal bleeding, chest pain, chills, swelling in the extremities, muscle pain, sweating, itching, acne, and feeling unwell (malaise).

Both Lialda and Delzicol may interact with mercaptopurine or aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs).

Lialda may also interact with azathioprine, pentamidine, tacrolimus, amphotericin B, antibiotics, antiviral medicines, or cancer medicines.

Delzicol may also interact with other drugs that can harm the kidneys.

What Are Possible Side Effects of Lialda?

Common side effects of Lialda include:

  • nausea,
  • vomiting,
  • stomach cramps,
  • diarrhea,
  • gas,
  • fever,
  • sore throat,
  • flu-like symptoms,
  • constipation,
  • headache,
  • dizziness,
  • tired feeling, or
  • skin rash.

Contact your doctor if you experience serious side effects of Lialda including:

  • severe stomach pain,
  • fever,
  • headache, and
  • bloody diarrhea.

What Are Possible Side Effects of Delzicol?

Common side effects of Delzicol include:

  • abdominal pain,
  • belching,
  • headache,
  • back pain,
  • dizziness,
  • diarrhea,
  • rash,
  • upset stomach,
  • indigestion,
  • nasal inflammation,
  • runny or stuffy nose,
  • flu syndrome,
  • cough,
  • gas,
  • vomiting,
  • fever,
  • fatigue,
  • joint pain and swelling (arthritis),
  • constipation,
  • gastrointestinal bleeding,
  • chest pain,
  • chills,
  • swelling in the extremities,
  • muscle pain,
  • sweating,
  • itching,
  • acne, and
  • feeling unwell (malaise).

What Is Lialda?

Lialda (mesalamine) is an anti-inflammatory agent used to treat ulcerative colitis, proctitis, and proctosigmoiditis, and also to prevent the symptoms of ulcerative colitis from recurring.

What Is Delzicol?

Delzicol (mesalamine) is an aminosalicylate used to treat mildly to moderately active ulcerative colitis (UC) and to maintain remission of UC.

What Drugs Interact With Lialda?

Lialda may interact with azathioprine or mercaptopurine, pentamidine, tacrolimus, amphotericin B, antibiotics, antiviral medicines, cancer medicine, aspirin or other NSAIDs. Tell your doctor all medications you are taking. Lialda is not expected to be harmful to a fetus. Tell your doctor if you are pregnant or plan to become pregnant during treatment. This medication can pass into breast milk and may harm a nursing baby. Do not use this medication if you are breastfeeding.

What Drugs Interact With Delzicol?

Nephrotoxic agents, or drugs that can be harmful to the kidneys such as nonsteroidal anti-inflammatory drugs (NSAIDs), may interact with Delzicol. Doctors should carefully evaluate the risks and benefits of Delzicol in patients with known kidney dysfunction or patients with a history of kidney disease. Delzicol may interact with arsenic trioxide, chloroquine or halofantrine, cyclosporine, droperidol, narcotics, vinblastine, antibiotics, medicines to treat psychiatric disorders, or heart rhythm medicines. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Delzicol. Delzicol has not been studied in pregnant women. Doctors should carefully evaluate the risks and benefits when giving Delzicol to a breastfeeding mother.

How Should Lialda Be Taken?

The recommended dosage of Lialda for the induction of remission in adult patients with active, mild to moderate ulcerative colitis is two to four 1.2 g tablets taken once daily with a meal for a total daily dose of 2.4 g or 4.8 g. The recommended dosage for the maintenance of remission is two 1.2 g tablets taken once daily with a meal for a total daily dose of 2.4 g.

How Should Delzicol Be Taken?

Delzicol is available as a delayed-release capsule in 400 mg strength. For the treatment of mildly to moderately active ulcerative colitis, patients should take 800mg of Delzicol, three times daily. For the maintenance of remission of ulcerative colitis, patients should take 1.6g (four capsules) daily, in divided doses. Delzicol should be swallowed whole without cutting, breaking, or chewing, and should be taken 1-2 hours after a meal.

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