Fetroja vs. Keflex

• Are Keflex and Fetroja the Same Thing?
• What Are Possible Side Effects of Fetroja?
• What Are Possible Side Effects of Keflex?
• What is Fetroja?
• What is Keflex?
• What Drugs Interact with Fetroja?
• What Drugs Interact with Keflex?
• How Should Fetroja Be Taken?
• How Should Keflex Be Taken?

Fetroja (cefiderocol) and Keflex (cephalexin) are cephalosporin antibiotics used to treat urinary tract infections (UTIs).

Fetroja is used for the treatment of complicated urinary tract infections (cUTI), including pyelonephritis caused by susceptible Gram-negative microorganisms.

Keflex is also used to treat various other bacterial infections, and before dental procedures in patients identified with certain heart-related conditions to prevent bacterial infections of the heart known as endocarditis.

Side effects of Fetroja and Keflex that are similar include diarrhea, rash, headache, nausea, and vomiting.

Side effects of Fetroja that are different from Keflex include infusion site reactions, constipation, candidiasis (oral thrush or vaginal yeast infections), cough, elevations in liver tests, and low blood potassium (hypokalemia).

Side effects of Keflex that are different from Fetroja include dizziness, tiredness, stomach upset, abdominal pain, joint pain, vaginal itching or discharge, itching, and swelling.

Fetroja may interact with other drugs.

Keflex may interact with blood thinners, metformin, and probenecid.

Common side effects of Fetroja include:

• diarrhea,
• infusion site reactions,
• constipation,
• rash,
• candidiasis (oral thrush or vaginal yeast infections),
• cough,
• elevations in liver tests,
• headache,
• low blood potassium (hypokalemia),
• nausea, and
• vomiting

Common side effects of Keflex include:

• diarrhea,
• dizziness,
• tiredness,
• headache,
• stomach upset,
• abdominal pain,
• joint pain,
• vaginal itching or discharge,
• nausea,
• vomiting,
• itching,
• swelling, and
• rash.

Fetroja (cefiderocol) is a cephalosporin antibacterial used to treat patients 18 years of age or older who have limited or no alternative treatment options, for the treatment of complicated urinary tract infections (cUTI), including pyelonephritis caused by susceptible Gram-negative microorganisms.

Keflex (cephalexin) is a cephalosporin antibiotic prescribed to treat bacterial infections. Keflex is also used before dental procedures in patients identified with certain heart-related conditions to prevent bacterial infections of the heart known as endocarditis. Keflex is available as a generic drug.

Fetroja may interact with other medicines.

Tell your doctor all medications and supplements you use.

Keflex and amoxicillin may interact with probenecid and blood thinners.

Keflex may also interact with metformin.

The dose of Fetroja for injection is 2 grams administered every 8 hours by intravenous (IV) infusion over 3 hours in patients with creatinine clearance (CLcr) 60 to 119 mL/min.

Keflex dosage depends on the condition being treated. Keflex should be used with caution in patients who have kidney disease and those who report a history of penicillin allergy.