Evenity vs. Boniva

• Are Evenity and Boniva the Same Thing?
• What Are Possible Side Effects of Evenity?
• What Are Possible Side Effects of Boniva?
• What Is Evenity?
• What Is Boniva?
• What Drugs Interact with Evenity?
• What Drugs Interact with Boniva?
• How Should Evenity Be Taken?
• How Should Boniva Be Taken?

Evenity (romosozumab-aqqg) and Boniva (ibandronate) are used to treat osteoporosis in postmenopausal women.

Evenity and Boniva belong to different drug classes. Evenity is a sclerostin inhibitor and Boniva is a bisphosphonate.

Side effects of Evenity and Boniva that are similar include joint pain, headache, and weakness.

Side effects of Evenity that are different from Boniva include muscle spasms, swelling of extremities, neck pain, insomnia, and numbness and tingling sensation.

Side effects of Boniva that are different from Evenity include back pain, eye redness or swelling, diarrhea, flu-like symptoms, nausea or stomach upset, pain in your arms or legs, redness or swelling where Boniva was injected, allergic reaction, indigestion, vomiting, dizziness, spinning sensation (vertigo), upper respiratory infection, pneumonia, and urinary tract infection (UTI).

Evenity may interact with other drugs.

Boniva may interact with products containing calcium, aluminum, magnesium, or iron (such as antacids, supplements or vitamins); and aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs).

Common side effects of Evenity include:

• joint pain,
• headache,
• muscle spasms,
• swelling of extremities,
• weakness,
• neck pain,
• insomnia,
• numbness and
• tingling sensation

Common side effects of Boniva include:

• back pain,
• headache,
• redness or swelling of your eyes,
• diarrhea,
• flu-like symptoms,
• nausea or stomach upset,
• pain in your arms or legs,
• redness or swelling where Boniva was injected,
• weakness,
• allergic reaction,
• indigestion,
• vomiting,
• joint pain,
• dizziness,
• spinning sensation (vertigo),
• upper respiratory infection,
• pneumonia, or
• urinary tract infection.

Evenity (romosozumab-aqqg) is a sclerostin inhibitor indicated for the treatment of osteoporosis in postmenopausal women at high risk for fracture, defined as a history of osteoporotic fracture, or multiple risk factors for fracture; or patients who have failed or are intolerant to other available osteoporosis therapy.

Boniva (ibandronate) is a bisphosphonate drug that alters the cycle of bone formation and breakdown in the body used to treat or prevent osteoporosis in women after menopause. Boniva slows bone loss while increasing bone mass, which may prevent bone fractures.

Evenity may interact with digoxin. Tell your doctor all medication

Evenity may interact with other drugs. Tell your doctor all medications and supplements you use. Evenity is not recommended for use in women of reproductive potential so it is not intended for use by women who are pregnant or breastfeeding.

Boniva may interact with aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs).

Boniva may also interact with products containing calcium, aluminum, magnesium, or iron (such as antacids, supplements or vitamins).

A healthcare provider can administer 210 mg Evenity subcutaneously once every month for 12 doses in the abdomen, thigh, or upper arm. Two separate subcutaneous injections are needed to administer the total dose of 210 mg Evenity.

The dose of Boniva is one 150 mg tablet taken once monthly on the same date each month.