Exforge vs. Twynsta

• Are Exforge and Twynsta the Same Thing?
• What Are Possible Side Effects of Exforge?
• What Are Possible Side Effects of Twynsta?
• What Is Exforge?
• What Is Twynsta?
• What Drugs Interact with Exforge?
• What Drugs Interact with Twynsta?
• How Should Exforge Be Taken?
• How Should Twynsta Be Taken?

Exforge (amlodipine and valsartan) and Twynsta (amlodipine and telmisartan) are combinations of a calcium channel blocker and an angiotensin II receptor antagonist used to treat high blood pressure (hypertension).

Exforge is usually given after other drugs have been tried without successful treatment of hypertension.

Side effects of Exforge and Twynsta that are similar include dizziness or lightheadedness as your body adjusts to the medication and flushing (warmth, redness, or tingly feeling).

Side effects of Exforge that are different from Twynsta include spinning sensation and cold symptoms (such as runny or stuffy nose, sneezing, and sore throat).

Side effects of Twynsta that are different from Exforge include swelling hands/ankles/feet, drowsiness, tired feeling, back pain, nausea, diarrhea, or vomiting.

Both Exforge and Twynsta may interact with lithium, potassium supplements or salt substitutes, diuretics (water pills), “statin” drugs, medicines to prevent organ transplant rejection, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Exforge may also interact with alcohol, heart medications, vitamin or mineral supplements that contain potassium, other medications that lower blood pressure, other cholesterol medications, cyclosporine, ritonavir, antibiotics, and antifungals.

Twynsta may also interact with aliskiren, ramipril, drugs that may increase potassium levels, cough-and-cold products, diet aids, digoxin, and ACE inhibitors.

Common side effects of Exforge include:

• dizziness,
• spinning sensation, or lightheadedness as your body adjusts to the medication.

Other side effects of Exforge include flushing, and cold symptoms such as runny/stuffy nose, sneezing, and sore throat.

Tell your doctor if you have serious side effects of Exforge including:

• swelling hands/ankles/feet,
• fainting,
• fast heartbeat,
• unusual change in the amount of urine,
• symptoms of a high potassium blood level (such as muscle weakness, slow/irregular heartbeat), or
• signs of infection (such as fever, chills, persistent sore throat).

Common side effects of Twynsta include:

• dizziness or lightheadedness as your body adjusts to the medication.

Other side effects of Twynsta include:

• swelling hands/ankles/feet,
• flushing (warmth, redness, or tingly feeling),
• drowsiness,
• tired feeling,
• back pain,
• nausea,
• diarrhea, or
• vomiting.

Tell your doctor if you have serious side effects of Twynsta including:

• fainting,
• fast/pounding/irregular heartbeat,
• unusual changes in the amount of urine, or
• symptoms of a high potassium blood level (such as muscle weakness, slow/irregular heartbeat).

Exforge (amlodipine and valsartan) is a combination of a calcium channel blocker and an angiotensin II receptor antagonist used to treat high blood pressure (hypertension). Exforge is usually given after other drugs have been tried without successful treatment of hypertension.

Twynsta (telmisartan/amlodipine) is a combination of an angiotensin receptor blocker and a calcium channel blocker used to treat high blood pressure (hypertension).

Exforge may interact with heart medication, potassium supplements or salt substitutes, diuretics (water pills), or other medications that lower blood pressure. Tell your doctor all medications you are taking. Exforge is not recommended for use during pregnancy due to the risk for harm to a fetus. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Twynsta may interact with aliskiren, lithium, ramipril, drugs that may increase potassium levels, cough-and-cold products, diet aids, or NSAIDs. Tell your doctor all medications and supplements you use.

Exforge (ziprasidone HCl) is available as capsules and Exforge (ziprasidone mesylate) is available as an injection for intramuscular use.

Exforge Capsules should be administered at an initial daily dose of 20 mg twice daily with food. For intramuscular dosing, the recommended dose of Exforge is 10 mg to 20 mg administered as required up to a maximum dose of 40 mg per day.

The maximum recommended dose of Twynsta tablets is 80/10 mg once daily.