How Does Ophthalmic Netarsudil Work?

Ophthalmic netarsudil is a medication used to reduce the pressure inside the eye (intraocular pressure). Netarsudil reduces aqueous humor production, and increases its outflow by blocking the activity of an enzyme known as rho kinase.

Aqueous humor is a clear fluid that fills the space between the cornea and the lens in the eye. Imbalance in the inflow and outflow of aqueous humor can affect the intraocular pressure.

Ophthalmic netarsudil is a solution topically administered in the eye to reduce intraocular pressure in eye conditions such as:

• Open-angle glaucoma: Glaucoma is a degenerative eye disease that damages the optic nerve. Open-angle glaucoma is the most common type of glaucoma, in which the drainage angle of aqueous humor is open but the drainage channels are partially blocked.
• Elevated intraocular pressure: Increased intraocular pressure due to imbalance in aqueous humor production and drainage.

Side effects of ophthalmic netarsudil may include:

• Dilation of blood vessels in the eye (ocular hyperemia)
• Corneal deposits (cornea verticillata)
• Instillation site pain and redness (erythema)
• Conjunctival hemorrhage
• Corneal staining
• Blurred vision
• Increased tearing
• Erythema of eyelid
• Reduced visual acuity

Information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

Generic and brand names of ophthalmic netarsudil include:

• netarsudil ophthalmic
• Rhopressa