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Definition of Journal of Clinical Investigation

Medically reviewed by Min Clinic Staff | Updated: January 2026

Journal of Clinical Investigation: (JCI) A highly regarded journal of medical science that publishes "biologically significant findings of clinical relevance." The JCI is the journal of the American Society for Clinical Investigation, an honor society of physician-scientists, physicians who are at the bedside, at the research bench, at the blackboard translating findings in the laboratory into the advancement of clinical medicine.