Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of End-stage renal disease

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

End-stage renal disease: ESRD. Chronic irreversible renal failure.

Also known as Chronic Kidney Disease Stage 6 or CKD 6. The state where renal replacement therapy is needed, either dialysis or transplant.

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