Definition of Atypical Teratoid Rhabdoid Tumor (ATRT)

Atypical teratoid rhabdoid tumor (ATRT) is a very rare, fast-growing central nervous system (brain or spinal cord) tumor. Most ATRTs are linked to changes in a gene known as SMARCB1 (also called INI1). Symptoms and signs depend on the exact location of the tumor within the brain and can include morning headaches, vomiting, problems with balance and coordination, and increased head size in infants. ATRTs can occur in both children and adults. The condition is extremely rare, and only about 58 people are diagnosed with ATRT per year in the U.S.