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Definition of Circadian rhythm disorder
Medically reviewed by Min Clinic Staff | Updated: January 2026
Circadian rhythm disorder: Disorders caused by the malfunctioning of the circadian system, or biological clock. A person's circadian rhythm is an internal biological clock that regulates a variety of body processes according to an approximate 24-hour period. All circadian rhythm disorders have in common the disruption of the normal sleep-wake cycle. Circadian rhythm disorders can be transient, such as jet lag, illness, and altered sleep cycle due to shift work. Chronic circadian rhythm disorders include delayed sleep-phase syndrome (DSPS), advanced sleep-phase syndrome (ASPS), and irregular sleep-wake cycle.