Definition of Epidermolysis bullosa simplex

Epidermolysis bullosa simplex: A variant of epidermolysis bullosa.

Epidermolysis bullosa simplex (EBS) usually begins with blistering that is evident at birth or shortly afterward. In a localized, mild form of EBS called Weber-Cockayne, blisters rarely extend beyond the feet and hands. In some subtypes of EBS, the blisters occur over widespread areas of the body.