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Definition of Typhus
Medically reviewed by Min Clinic Staff | Updated: January 2026
Typhus: One of a group of acute infections caused by rickettsiae, transmitted by arthropods (lice, fleas, mites), and characterized by severe headache, chills, high fever, stupor, and a rash. The four main entities making up the group are epidemic typhus, its recrudescent form (Brill-Zinsser disease), murine typhus, and scrub typhus. Called also typhus fever. See also: Brill-Zinsser disease; Epidemic typhus; Murine typhus; Scrub typhus.