Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.

Definition of Phospholipase

Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026

Phospholipase: An enzyme that catalyzes the splitting of a phospholipid molecule by the addition of water. Also called a lecithinase.

There are a number of phospholipases. They are grouped on the basis of the specific chemical bond they split. The phospholipases include phospholipase A1 (PLA1), phospholipase A2 (PLA2), phospholipase C, and phospholipase D.

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