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Definition of Saccharin
Medically reviewed by Min Clinic Staff | Updated: January 2026
Saccharin: An artificial sweetener which diluted in water is 200-700 times sweeter than the sugar sucrose. (The chemical name for saccharin is o-sulfabenzamide; 2,3-dihydro-3-oxobenzisosulfonazole).
The US government removed saccharin from its list of potential cancer-causing agents in 2000 because tests show that it causes bladder cancers in rats through a mechanism unrelated to human physiology. There is no evidence that it causes tumors in humans.