Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Mitochondrial genome
Medically reviewed by Dr. Otari Nergadze, Neurosurgeon | Updated: January 2026
Mitochondrial genome: The sum of the genetic information contained in the chromosome of the mitochondrion, a structure located in the cytoplasm outside the nucleus of the cell. The mitochondrial genome is composed of mitochondrial DNA (mDNA), a double-stranded circular molecule that contains a limited number of genes. During fertilization, mDNA is transmitted only by the mother. Together, the mitochondrial genome and the chromosomal genome constitute the entire human genome.
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