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Detigon: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Detigon - General Information

Detigon is a centrally-acting cough suppressant available in Canada under the trade name Ulone. It is not available in the United States.

 

Pharmacology of Detigon

Detigon (or Clofedanol) is a centrally-acting cough suppressant. It has local anesthetic and antihistamine properties, and may have anticholinergic effects at high doses.

 

Additional information about Detigon

Detigon Indication: Used in the treatment of dry cough. Mechanism Of Action: Suppresses the cough reflex by a direct effect on the cough center in the medulla of the brain. Drug Interactions: Not Available Food Interactions: Take without regard to meals.Avoid alcohol. Generic Name: Chlophedianol Synonyms: Chlofedanol; Clofedano; Clofedanol; Clofedanolum [inn-latin]; Clofedianolo [italian]; Clophedianol base; Alpha-(dimethylaminoethyl)-o-chlorobenzhydrol; 1-Phenyl-1-(o-chlorophenyl)-3-dimethylaminopropanol; 1-(2-Chlorophenyl)-3-(dimethylamino)-1-phenyl-1-propanol; 2-Chloro-alpha-(2-(dimethylamino)ethyl)benzhydrol Drug Category: Antitussive Agents; Antihistamines; Anesthetics, Local Drug Type: Small Molecule; Approved Other Brand Names containing Chlophedianol: Calmotusin; Dencyl; Tussistop; Ulone; Coldrin; Detigon; Eutus; Ulo; Absorption: Not Available Toxicity (Overdose): Not Available Protein Binding: Not Available Biotransformation: Hepatic. Half Life: Not Available Dosage Forms of Detigon: Syrup Oral Chemical IUPAC Name: 1-(2-chlorophenyl)-3-dimethylamino-1-phenylpropan-1-ol Chemical Formula: C17H20ClNO Chlophedianol on Wikipedia: https://en.wikipedia.org/wiki/Clofedanol Organisms Affected: Humans and other mammals