Desocort
Desocort - General Information
A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses. [PubChem]
Pharmacology of Desocort
Desocort is a synthetic nonfluorinated corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents.
Desocort for patients
Patients using topical corticosteroids should receive the following information and instructions:
- This medication is to be used as directed by the physician. It is for external use only. Avoid contact with the eyes.
- This medication should not be used for any disorder other than that for which it was prescribed.
- The treated skin area should not be bandaged or otherwise covered or wrapped so as to be occlusive unless directed by the physician.
- Patients should report to their physician any signs of local adverse reactions.
Desocort Interactions
Desocort Contraindications
DesOwen Cream, Ointment and Lotion are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparations.
Additional information about Desocort
Desocort Indication: For the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatose.
Mechanism Of Action: Like other topical corticosteroids, desonide has anti-inflammatory, antipruritic and vasoconstrictive properties. The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Desonide
Synonyms: Not Available
Drug Category: Anti-inflammatory Agents
Drug Type: Small Molecule; Approved; Investigational
Other Brand Names containing Desonide: Desocort; Desowen; Tridesilon;
Absorption: Topical corticosteroids can be absorbed from normal intact skin, inflammation and/or other disease processes in the skin may increase percutaneous absorption.
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Desocort: Ointment Topical
Lotion Topical
Cream Topical
Chemical IUPAC Name: Not Available
Chemical Formula: C24H32O6
Desonide on Wikipedia: https://en.wikipedia.org/wiki/Desonide
Organisms Affected: Humans and other mammals
