Decabid
Decabid - General Information
Decabid is a rarely used antidysrhythmic. Decabid has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics.
Pharmacology of Decabid
Decabid is a rarely used antidysrhythmic. Decabid has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics.
Decabid for patients
Decabid Interactions
Decabid Contraindications
Contraindicated in right bundle branch block, cardiogenic shock, hypersensitivity, and second or third degree AV block.
Additional information about Decabid
Decabid Indication: For the treatment of life-threatening dysrhythmias and sustained ventricular tachycardia.
Mechanism Of Action: Decabid acts on sodium channels on the neuronal cell membrane, limiting the spread of seizure activity and reducing seizure propagation. The antiarrhythmic actions are mediated through effects on sodium channels in Purkinje fibers.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Indecainide
Synonyms: Ricainid; Ricainide; Indecainidum [Latin]; Indecainida [Spanish]; 9-(3-(Isopropylamino)propyl)-9-fluorenylcarboxamid; 9-(3-(Isopropylamino)propyl))fluorene-9-carboxamide
Drug Category: Antidysrhythmic Agents; Sodium channel blockers
Drug Type: Small Molecule; Approved
Other Brand Names containing Indecainide: Decabid;
Absorption: Nearly complete following oral administration.
Toxicity (Overdose): When given orally to either young adult rats or mice, the LD50 was 100 mg/kg. Symptoms of overdose include nausea and vomiting, convulsions, hypotension, bradycardia, syncope, extreme widening of the QRS complex, widening of the QT interval, widening of the PR interval, ventricular tachycardia, AV nodal block, asystole, bundle branch block, cardiac failure, and cardiac arrest.
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Decabid: Not Available
Chemical IUPAC Name: 9-[3-(propan-2-ylamino)propyl]fluorene-9-carboxamide
Chemical Formula: C20H24N2O
Indecainide on Wikipedia: Not Available
Organisms Affected: Humans and other mammals