Celontin

Celontin - General Information

Mesuximide (or methsuximide) is an anticonvulsant medication. It is sold by Pfizer under the name Petinutin. [Wikipedia]

Pharmacology of Celontin

Not Available

Additional information about Celontin

Celontin Indication: For the control of absence (petit mal) seizures that are refractory to other drugs.
Mechanism Of Action: Celontin suppresses the paroxysmal three cycle per second spike and wave activity associated with lapses of consciousness which is common in absence (petit mal) seizures. The frequency of epileptiform attacks is reduced, apparently by depression of the motor cortex and elevation of the threshold of the central nervous system to convulsive stimuli.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Methsuximide
Synonyms: Mesuximide; Mesuximidum [inn-latin]; Mesuximida [inn-spanish]; Methsuximid; Metosuccimmide [DCIT]; Metsuccimide; N,2-Dimethyl-2-phenylsuccinimide; N-methyl-alpha-methyl-alpha-phenylsuccinimide; Alpha-methylphensuximide; Alpha-methyl-alpha-phenyl n-methyl succinimide; 1,3-Dimethyl-3-phenylsuccinimide; 1,3-Dimethyl-3-phenyl-pyrrolidin-2,5-dione; 1,3-Dimethyl-3-phenyl-2,5-pyrrolidinedione; 1,3-Dimethyl-3-phenyl-2,5-dioxopyrrolidine; (RS)-1,3-Dimethyl-3-phenyl-2,5-pyrrolidindion
Drug Category: Anticonvulsants
Drug Type: Small Molecule; Approved

Other Brand Names containing Methsuximide: Petinutin; Celontin;
Absorption: Not Available
Toxicity (Overdose): Acute overdoses may produce nausea, vomiting, and CNS depression including coma with respiratory depression. Levels greater than 40 &
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: 1.4-2.6 hours for mesuximide and 28-38 hours for the active metabolite.
Dosage Forms of Celontin: Capsule Oral
Chemical IUPAC Name: 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione
Chemical Formula: C12H13NO2
Methsuximide on Wikipedia: https://en.wikipedia.org/wiki/Methsuximide
Organisms Affected: Humans and other mammals