Bambec: Full Drug Profile
Bambec - General Information
Bambec is a long acting beta-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline.
Pharmacology of Bambec
Bambec is a long acting beta2-adrenoceptor agonist used in the treatment of asthma. It is a prodrug of terbutaline.
Additional information about Bambec
Bambec Indication: For the prevention and reversal of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema. Mechanism Of Action: The pharmacologic effects of bambuterol are at least in part attributable to stimulation through beta-adrenergic receptors of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic AMP. Increased cyclic AMP levels are associated with relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells. Drug Interactions: Not Available Food Interactions: Not Available Generic Name: Bambuterol Synonyms: Bambuterol hydrochloride Drug Category: Bronchodilator Agents; Adrenergic beta-Agonists; Tocolytic Agents; Sympathomimetics Drug Type: Small Molecule; Approved Other Brand Names containing Bambuterol: Bambec; Oxeol; Absorption: Bioavailability is 20% following oral administration. Toxicity (Overdose): Not Available Protein Binding: Not Available Biotransformation: Hepatic, extensive. Further metabolized to terbutaline by plasma cholinesterase. Half Life: 13 hours for bambuterol and 21 hours for the primary active metabolite terbutaline. Dosage Forms of Bambec: Tablet Oral Chemical IUPAC Name: [3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate Chemical Formula: C18H29N3O5 Bambuterol on Wikipedia: https://en.wikipedia.org/wiki/Bambuterol Organisms Affected: Humans and other mammals
