Apo-Trifluoperazine

Apo-Trifluoperazine - General Information

A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.

Pharmacology of Apo-Trifluoperazine

Apo-Trifluoperazine is a trifluoro-methyl phenothiazine derivative intended for the management of schizophrenia and other psychotic disorders. Apo-Trifluoperazine has not been shown effective in the management of behaviorial complications in patients with mental retardation.

Apo-Trifluoperazine for patients

Apo-Trifluoperazine Interactions

No information provided.

Apo-Trifluoperazine Contraindications

A known hypersensitivity to phenothiazines, comatose or greatly depressed states due to central nervous system depressants and, in cases of existing blood dyscrasias, bone marrow depression and pre-existing liver damage.

Additional information about Apo-Trifluoperazine

Apo-Trifluoperazine Indication: For the treatment of anxiety disorders, depressive symptoms secondary to anxiety and agitation.
Mechanism Of Action: Apo-Trifluoperazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Trifluoperazine
Synonyms: Not Available
Drug Category: Antipsychotics; Antiemetics; Phenothiazines
Drug Type: Small Molecule; Approved

Other Brand Names containing Trifluoperazine: Apo-Trifluoperazine; Eskazine; Eskazinyl; Fluoperazine; Jatroneural; Modalina; Novo-Trifluzine; PMS Trifluoperazine; Stelazine; Stelazine Concentrate; Stellazine; Synklor; Terfluzine; Trazine; Trifluoperazin; Trifluoperazina; Trifluoperazine Dihydrochloride; Trifluoperazine HCl; Trifluoperazine Hydrochloride; Trifluoromethylperazine; Trifluoroperazine; Trifluoroperazine Dihydrochloride; Trifluoroperazine Hydrochloride; Trifluperazine; Triflurin; Trifluroperizine; Triftazin; Triftazine; Triperazine; Triphtazin; Triphtazine; Triphthasine; Triphthazine; Triphthazine Dihydrochloride; Tryptazine; Tryptazine Dihydrochloride;
Absorption: Not Available
Toxicity (Overdose): Symptoms of overdose include agitation, coma, convulsions, difficulty breathing, difficulty swallowing, dry mouth, extreme sleepiness, fever, intestinal blockage, irregular heart rate, low blood pressure, and restlessness.
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Apo-Trifluoperazine: Tablet Oral
Syrup Oral
Chemical IUPAC Name: 10-[3-(4-methylpiperazin-1-yl)propyl]-2-(trifluoromethyl)phenothiazine
Chemical Formula: C21H24F3N3S
Trifluoperazine on Wikipedia: https://en.wikipedia.org/wiki/Trifluoperazine
Organisms Affected: Humans and other mammals