Norm of Ultrafast (UFP) and Fine-Needle Pap Smear Aspiration
Normal cells and structure for the area biopsied. Absence of tumor cells or abnormalities of the cell nucleus.
Usage of Ultrafast (UFP) and Fine-Needle Pap Smear Aspiration
Adenocarcinoma, of various organs; squamous cell carcinoma; neuroendocrine carcinomas; clear cell–type renal cell carcinoma; schwannoma; lymphoid hyperplasia, with small round lymphocytes, small cleaved lymphocytes, large noncleaved lymphocytes, and histocytes (macrophages). Breast-tissue lesions, thyroid lesions, Hürthle cell carcinoma, and colloid nodule with hemorrhagic degeneration.
Description of Ultrafast (UFP) and Fine-Needle Pap Smear Aspiration
This procedure involves fine-needle aspiration for cytologic evaluation and may be performed intraoperatively or during a colposcopic examination (see Colposcopy). The ultrafast technique is particularly useful when a quick result is important. The method is particularly advantageous for looking at the cell nucleus because it provides the cytologist or histologist with a clear, stained view of the cell and organelles.
Professional Considerations of Ultrafast (UFP) and Fine-Needle Pap Smear Aspiration
Consent form IS required for all fine-needle aspiration biopsy procedures. For specimens taken during surgery, the client gives consent for the surgical procedure.
- Obtain clear glass slides, a syringe, and 18-gauge needles; Choplin jars; normal saline; and 95% ethyl alcohol for storage and transport to the laboratory.
- Notify the laboratory for on-site processing, staining, handling, and consultative interpretation of the specimen.
- Just before beginning the procedure, take a “time out” to verify the correct client, procedure, and site.
- Depends on the body site and location of the area for biopsy. Some clients will be prepared for surgery and taken to an operating room.
- Ambulatory care and ward procedures may require local anesthesia.
- The skin is prepared for the procedure.
- Needle aspiration of the tissue is obtained; sometimes a special procedure such as fluoroscopy or isolation of a nodule is required. The specimen is taken with a sterile technique, and smears are made on the clear microscope slides. It is air-dried and processed for 30 seconds in normal saline and then in 95% ethyl alcohol and sent immediately to the laboratory for processing, or the cytologist present during the procedure handles the specimen. The developers suggest that fine-needle aspirations for cytology follow this procedure: (1) prepare several clear glass slides and air-dry; (2) stain and process the ultrafast slide; (3) save the other slides for laboratory use for other methods such as the Diff-Quik stain, which has other advantages for the final diagnosis.
- The specimen is carefully labeled and transported immediately to the cytology laboratory.
- Apply a dry, sterile dressing over the site.
- Monitor for bleeding at the site.
- Give postsurgical care as appropriate.
Client and Family Teaching
1. Call the physician for signs of infection at the procedure site: increasing pain, redness, swelling, purulent drainage, or for temperature >101 degrees F (38.3 degrees C).
2. Results are normally available within 24 hours.
Factors That Affect Results
- Inappropriate processing.
- Total turn-around time for these specimens may be as little as 30 minutes.
- See also Pap smear.