Ultrafast (UFP) and Fine-Needle Pap Smear Aspiration

Norm of Ultrafast (UFP) and Fine-Needle Pap Smear Aspiration

Normal cells and structure for the area biopsied. Absence of tumor cells or abnormalities of the cell nucleus.


Usage of Ultrafast (UFP) and Fine-Needle Pap Smear Aspiration

Adenocarcinoma, of various organs; squamous cell carcinoma; neuroendocrine carcinomas; clear cell–type renal cell carcinoma; schwannoma; lymphoid hyperplasia, with small round lymphocytes, small cleaved lymphocytes, large noncleaved lymphocytes, and histocytes (macrophages). Breast-tissue lesions, thyroid lesions, Hürthle cell carcinoma, and colloid nodule with hemorrhagic degeneration.


Description of Ultrafast (UFP) and Fine-Needle Pap Smear Aspiration

This procedure involves fine-needle aspiration for cytologic evaluation and may be performed intraoperatively or during a colposcopic examination (see Colposcopy). The ultrafast technique is particularly useful when a quick result is important. The method is particularly advantageous for looking at the cell nucleus because it provides the cytologist or histologist with a clear, stained view of the cell and organelles.


Professional Considerations of Ultrafast (UFP) and Fine-Needle Pap Smear Aspiration

Consent form IS required for all fine-needle aspiration biopsy procedures. For specimens taken during surgery, the client gives consent for the surgical procedure.

  1. Obtain clear glass slides, a syringe, and 18-gauge needles; Choplin jars; normal saline; and 95% ethyl alcohol for storage and transport to the laboratory.
  2. Notify the laboratory for on-site processing, staining, handling, and consultative interpretation of the specimen.
  3. Just before beginning the procedure, take a “time out” to verify the correct client, procedure, and site.



  1. Depends on the body site and location of the area for biopsy. Some clients will be prepared for surgery and taken to an operating room.
  2. Ambulatory care and ward procedures may require local anesthesia.
  3. The skin is prepared for the procedure.
  4. Needle aspiration of the tissue is obtained; sometimes a special procedure such as fluoroscopy or isolation of a nodule is required. The specimen is taken with a sterile technique, and smears are made on the clear microscope slides. It is air-dried and processed for 30 seconds in normal saline and then in 95% ethyl alcohol and sent immediately to the laboratory for processing, or the cytologist present during the procedure handles the specimen. The developers suggest that fine-needle aspirations for cytology follow this procedure: (1) prepare several clear glass slides and air-dry; (2) stain and process the ultrafast slide; (3) save the other slides for laboratory use for other methods such as the Diff-Quik stain, which has other advantages for the final diagnosis.


Postprocedure Care

  1. The specimen is carefully labeled and transported immediately to the cytology laboratory.
  2. Apply a dry, sterile dressing over the site.
  3. Monitor for bleeding at the site.
  4. Give postsurgical care as appropriate.


Client and Family Teaching

1. Call the physician for signs of infection at the procedure site: increasing pain, redness, swelling, purulent drainage, or for temperature >101 degrees F (38.3 degrees C).

2. Results are normally available within 24 hours.


Factors That Affect Results

  1. Inappropriate processing.


Other Data

  1. Total turn-around time for these specimens may be as little as 30 minutes.
  2. See also Pap smear.