Hoffmann’s Sign

Hoffmann’s Sign

Hoffmann’s sign or reflex is a digital reflex consisting of flexion of the thumb and index finger in response to snapping or flicking the distal phalanx of the middle finger, causing a sudden extension of the joint. Although sometimes a normal finding, for example in the presence of generalized hyperreflexia (anxiety, hyperthyroidism), it may be indicative of a corticospinal tract lesion above C5 or C6, particularly if present unilaterally.

Cross References

Trömner’s sign; Upper motor neurone (UMN) Syndrome