Gynecomastia

Gynecomastia

Gynecomastia is inappropriate breast development in males. It may be observed in chronic liver disease and in certain neurological diseases:

Excessive pituitary prolactin release secondary to impaired dopamine release from the hypothalamus due to local tumor or treatment with dopaminergic antagonist drugs (e.g., antipsychotic medications)
Kennedy’s syndrome (X-linked bulbospinal neuronopathy) Klinefelter’s syndrome
POEMS syndrome.