Colliers Sign

Collier’s Sign

Collier’s sign ("posterior fossa stare", "tucked lid" sign) is elevation and retraction of the upper eyelids, baring the sclera above the cornea, with the eyes in the primary position or looking upward. This may be seen with upper dorsal midbrain supranuclear lesions (e.g., "top of the basilar syndrome", Parinaud’s syndrome). There may be accompanying paralysis of vertical gaze (especially upgaze) and light-near pupillary dissociation. The sign is thought to reflect damage to the posterior commissure levator inhibitory fibers.

References

Collier J. Nuclear ophthalmoplegia with special reference to retraction of the lids and ptosis and to lesions of the posterior commissure. Brain1927; 50: 488-498
Galetta SL, Gray LG, Raps EC, Schatz NJ. Pretectal eyelid retraction and lag. Annals of Neurology 1993; 33: 554-557

Cross References

Lid retraction; Light-near pupillary dissociation; Parinaud’s syndrome