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Motegrity

  • Generic Name: prucalopride tablets
  • Brand Name: Motegrity
  • Drug Class: Prokinetic Agents

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  • Motegrity Patient Information Including Side Effects

    Brand Names: Motegrity

    Generic Name: prucalopride

    What is prucalopride (Motegrity)?

    Prucalopride is used to treat chronic idiopathic constipation (constipation without a known cause).

    Prucalopride may also be used for purposes not listed in this medication guide.

    What are the possible side effects of prucalopride (Motegrity)?

    Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

    Stop using prucalopride and call your doctor at once if you have:

    • unusual changes in mood or behavior;
    • ongoing or worsening depression;
    • thoughts about suicide or hurting yourself; or
    • if you feel sad or hopeless.

    Common side effects may include:

    • nausea, vomiting, diarrhea;
    • stomach pain, bloating, gas;
    • headache;
    • dizziness; or
    • feeling tired.

    This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    What is the most important information I should know about prucalopride (Motegrity)?

    You should not use prucalopride if you have a blockage in your intestines, Crohn's disease, ulcerative colitis, or intestinal perforation.

    Motegrity Patient Information including How Should I Take

    What should I discuss with my healthcare provider before taking prucalopride (Motegrity)?

    You should not use prucalopride if you are allergic to it, or if you have:

    Tell your doctor if you have ever had:

    • kidney disease;
    • depression;
    • a mood disorder; or
    • suicidal thoughts.

    Tell your doctor if you are pregnant or breast-feeding.

    Prucalopride is not approved for use by anyone younger than 18 years old.

    How should I take prucalopride (Motegrity)?

    Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

    You may take prucalopride with or without food.

    Store prucalopride in the original container at room temperature, away from moisture and heat.

    Motegrity Patient Information including If I Miss a Dose

    What happens if I miss a dose (Motegrity)?

    Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

    What happens if I overdose (Motegrity)?

    Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

    Overdose may cause severe diarrhea.

    What should I avoid while taking prucalopride (Motegrity)?

    Follow your doctor's instructions about any restrictions on food, beverages, or activity.

    What other drugs will affect prucalopride (Motegrity)?

    Other drugs may affect prucalopride, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

    Where can I get more information (Motegrity)?

    Your pharmacist can provide more information about prucalopride.


    Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
    Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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