Educational Content: This article is for informational purposes only and does not constitute medical advice. Always consult a healthcare provider for diagnosis and treatment.
Definition of Megacolon
Medically reviewed by Min Clinic Staff | Updated: January 2026
Megacolon: An abnormally enlarged colon. Megacolon can arise as a serious congenital problem in the newborn, caused by abnormal innervation of the colon and frequently requiring surgery.