Olux-E

Olux-E (clobetasol propionate foam) is a topical (for the skin) steroid used to treat inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis. Common side effects of Olux-E include:

• application site reactions when Olux-E is first applied to the skin (skin rash, burning, itching, redness, irritation, or dryness),
• acne,
• unusual hair growth,
• "hair bumps" (folliculitis),
• cracking skin,
• thinning or softening of your skin,
• skin rash or irritation around your mouth,
• temporary hair loss,
• spider veins,
• changes in color of treated skin,
• blisters,
• pimples,
• crusting of treated skin, or
• stretch marks.

Tell your doctor if you have severe irritation of any treated skin, or if you show signs of absorbing Olux-E through your skin and have side effects including:

• blurred vision, or seeing halos around lights,
• mood changes,
• sleep problems (insomnia),
• weight gain,
• puffiness in your face,
• muscle weakness, or
• feeling tired.

The dose of Olux-E is to apply a thin layer of foam to the affected area(s) twice daily, morning and evening for up to 2 consecutive weeks; therapy should be discontinued when control has been achieved. The maximum weekly dose should not exceed 50 g or an amount greater than 21 capfuls per week. It is not likely that other drugs you take orally or inject will have an effect on topically applied Olux-E. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, and supplements you use. During pregnancy, Olux-E should be used only when prescribed. It is not known whether this drug passes into breast milk when applied to the skin. Similar medications pass into breast milk when taken by mouth. Consult your doctor before breastfeeding.

Our Olux-E (clobetasol propionate foam) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

 

Olux-E Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• worsening of your skin condition;
• redness, warmth, swelling, oozing, or severe irritation of any treated skin;
• blurred vision, tunnel vision, eye pain, or seeing halos around lights;
• high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or
• possible signs of absorbing this medicine through your skin--weight gain in your face and shoulders, slow wound healing, skin discoloration, thinning skin, increased body hair, tiredness, mood changes, menstrual changes, sexual changes.

Common side effects may include:

• burning, itching, swelling, or irritation of treated skin;
• dry or cracking skin;
• redness or crusting around your hair follicles;
• spider veins;
• stretch marks, thinning skin;
• rash or hives;
• acne; or
• temporary hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Olux-E (Clobetasol Propionate Foam)

 

Olux-E Professional Information

SIDE EFFECTS

Clinical Trials Experience

In controlled clinical trials involving 821 subjects exposed to Olux-E (clobetasol propionate foam) Foam and Vehicle Foam, the pooled incidence of local adverse reactions in trials for atopic dermatitis and psoriasis with Olux-E (clobetasol propionate foam) Foam was 1.9% for application site atrophy and 1.6% for application site reaction. Most local adverse events were rated as mild to moderate and they were not affected by age, race, or gender. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.

The following additional local adverse reactions have been reported with topical corticosteroids: folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, irritation, striae, and miliaria. They may occur more frequently with the use of occlusive dressings and higher potency corticosteroids, such as clobetasol propionate.

Cushing's syndrome has been reported in infants and adults as a result of prolonged use of topical clobetasol propionate formulations.

Postmarketing Experience

The following adverse reactions have been identified during post-approval use of clobetasol formulations: erythema, pruritus, burning, alopecia, and dryness.

Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Read the entire FDA prescribing information for Olux-E (Clobetasol Propionate Foam)