EryPed

What Is EryPed?

EryPed (erythromycin ethylsuccinate) is a macrolide antibiotic used to treat many different types of infections caused by bacteria. EryPed is available in generic form.

What Are Side Effects of EryPed?

Common side effects of EryPed include:

• nausea,
• vomiting,
• diarrhea,
• stomach pain or cramping,
• loss of appetite,
• mild heartburn,
• dizziness,
• headache,
• feeling tired,
• vaginal itching or discharge, or
• itching or skin rash

Dosage for EryPed

The usual adult dose of Eryped is 400 mg every 6 hours. In children, age, weight, and severity of the infection are used to determine the proper dosage. In mild to moderate infections in children, the usual dosage is 30 to 50 mg/kg/day in equally divided doses every 6 hours. For more severe infections this dosage may be doubled.

What Drugs, Substances, or Supplements Interact with EryPed?

Eryped may interact with bromocriptine, cilostazol, cyclosporine, digoxin, disopyramide, quinidine, sildenafil, tacrolimus, theophylline, verapamil, vinblastine, alprazolam, triazolam, blood thinners, carbamazepine, phenytoin, valproic acid, cholesterol-lowering medications, ergotamine, dihydroergotamine, or other antibiotics. Tell your doctor all medications and supplements you use.

EryPed During Pregnancy and Breastfeeding

Eryped should be used only when prescribed during pregnancy. This medication passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Eryped (erythromycin ethylsuccinate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

 

EryPed Consumer Information

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Call your doctor at once if you have:

• severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);
• headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;
• a seizure;
• hearing problems (rare);
• pancreatitis--severe pain in your upper stomach spreading to your back, nausea and vomiting; or
• liver problems--loss of appetite, stomach pain (upper right side), tiredness, easy bruising or bleeding, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Serious side effects may be more likely in older adults, including hearing loss, or a life-threatening fast heart rate.

Call your doctor if a baby using this medicine is vomiting or irritable with feeding.

Common side effects may include:

• severe stomach pain, diarrhea that is watery or bloody (even if it occurs months after your last dose);
• liver problems; or
• abnormal liver function tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for EryPed (Erythromycin Ethylsuccinate)

 

EryPed Professional Information

SIDE EFFECTS

The following clinically significant adverse reactions are described elsewhere in the labeling:

• Potential Risk of Myocardial Infarction with Long-Term Use [see WARNINGS AND PRECAUTIONS]
• Gastrointestinal-Related Adverse Reactions in Opioid-Tolerant Patients [see WARNINGS AND PRECAUTIONS]
• Risk of Serious Adverse Reactions in Patients with Severe Hepatic Impairment [see WARNINGS AND PRECAUTIONS]
• Risk of Serious Adverse Reactions in Patients with Complete Gastrointestinal Obstruction [see WARNINGS AND PRECAUTIONS]
• Risk of Serious Adverse Reactions in Pancreatic and Gastric Anastomoses [see WARNINGS AND PRECAUTIONS]

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be compared directly with rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice. The adverse event information from clinical trials does, however, provide a basis for identifying the adverse events that appear to be related to drug use and for approximating rates.

The data described below reflect exposure to ENTEREG 12 mg in 1,793 patients in 10 placebo-controlled studies. The population was 19 to 97 years old, 64% were female, and 84% were Caucasian; 64% were undergoing a surgery that included bowel resection. The first dose of ENTEREG was administered 30 minutes to 5 hours before the scheduled start of surgery and then twice daily until hospital discharge (or for a maximum of 7 days of postoperative treatment).

Among ENTEREG-treated patients undergoing surgeries that included a bowel resection, the most common adverse reaction (incidence ≥1.5%) occurring with a higher frequency than placebo was dyspepsia (ENTEREG, 1.5%; placebo, 0.8%). Adverse reactions are events that occurred after the first dose of study medication treatment and within 7 days of the last dose of study medication or events present at baseline that increased in severity after the start of study medication treatment.

Read the entire FDA prescribing information for EryPed (Erythromycin Ethylsuccinate)