Dosing and uses of Sodium lactate
Adult dosage forms and strengths
infusion solution
- 500mL
- 1000mL
Alkalinizing Agent
As directed by physician (based on severity of metabolic acidosis)
Pediatric dosage forms and strengths
infusion solution
- 500mL
- 1000mL
Alkalinizing Agent
As directed by physician (based on severity of metabolic acidosis)
Sodium lactate adverse (side) effects
Frequency not defined
Febrile response
Injection site infections
Phlebitis
Thrombosis
Extravasation
Hypervolemia
Warnings
Contraindications
Not for lactic acidosis
Cautions
CHF, severe renal impairment, edema with sodium retention
Metabolic or respiratory alkalosis
Pregnancy and lactation
Pregnancy category: C
Lactation: use caution
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Sodium lactate
Metabolism: lactate is converted in the liver into bicarbonate
Excretion: N/A
Mechanism of action
Lactate is converted into bicarbonate
Administration
IV Administration
NMT 300 mL/hr in adults
Do not use plastic containers in series connections
Use only non-vented set or vented set with vent closed
IV Incompatibilities
Additive: Na-bicarbonate
Storage
Store at 40°C or less
Protect from extreme heat & freezing
