Dosing and uses of Nystatin vaginal
Adult dosage forms and strengths
vaginal tablet
- 100,000 units
Vaginal Candidiasis
With applicator provided, insert 1 vaginal tablet into vagina qDay for 2 weeks
Pediatric dosage forms and strengths
vaginal tablet
- 100,000 units
Vaginal Candidiasis
Adolescents: As adults; with applicator provided, insert 1 vaginal tablet into vagina qDay for 2 weeks
Nystatin vaginal adverse (side) effects
Frequency not defined
Localized sensitization
Warnings
Contraindications
Hypersensitivity
Pregnancy and lactation
Pregnancy category: A
Lactation: Poorly distributed in breast milk
Pregnancy categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA: Information not available.
Pharmacology of Nystatin vaginal
Absorption: Systemic absorption unlikely; poorly absorbed from intact skin and mucous membranes
Mechanism of action
Antifungal agent; binds to sterols in cell membrane resulting in permeability changes and leakage of intracellular content
