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Symtuza Side Effects Center

Medically reviewed by Min Clinic Staff | Updated: January 2026
  • Generic Name: darunavir, cobicistat, emtricitabine, and tenofovir  alafenamide tablets
  • Brand Name: Symtuza

Symtuza (Darunavir, Cobicistat, Emtricitabine, and Tenofovir  Alafenamide Tablets) side effects drug center

 

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SIDE EFFECTS

 

Symtuza Side Effects Center

What Is Symtuza?

Symtuza (darunavir, cobicistat, emtricitabine, and tenofovir alafenamide) is a four-drug combination of a human immunodeficiency virus (HIV-1) protease inhibitor, a CYP3A inhibitor, and two HIV-1 nucleoside analog reverse transcriptase inhibitors, and is indicated as a complete regimen for the treatment of HIV-1 infection in adults who have no prior antiretroviral treatment history or who are virologically suppressed (HIV-1 RNA less than 50 copies per mL) on a stable antiretroviral regimen for at least 6 months and have no known substitutions associated with resistance to darunavir or tenofovir.

What Are Side Effects of Symtuza?

Common side effects of Symtuza include:

  • diarrhea,
  • rash,
  • nausea,
  • fatigue,
  • headache,
  • abdominal discomfort, and
  • gas

Dosage for Symtuza

The recommended dosage of Symtuza is one tablet taken once daily with food.

What Drugs, Substances, or Supplements Interact with Symtuza?

Symtuza may interact with:

  • other antiretroviral medications for the treatment of HIV-1 infection,