Norco 5-325

What Is Norco 5/325?

Norco 5/325 (hydrocodone acetaminophen and bitartrate) is an opioid analgesic and antitussive (cough suppressant) combined with a fever reducer and pain reliever and used to treat moderate to fairly severe pain. Norco 5/325 is available as a generic.

What Are Side Effects of Norco 5/325?

Common side effects of Norco 5/325 include:

• lightheadedness,
• nausea,
• vomiting,
• constipation,
• upset stomach,
• dizziness or drowsiness,
• anxiety,
• headache,
• mood changes,
• blurred vision,
• ringing in the ears, or
• dry mouth.

Dosage for Norco 5/325

The usual adult dosage of Norco 5/325 is one tablet every four to six hours as needed for pain. The total daily dosage should not exceed 6 tablets.

What Drugs, Substances, or Supplements Interact with Norco 5/325?

Norco 5/325 may interact with other narcotic pain medications, sedatives, tranquilizers, sleeping pills, muscle relaxers, other medicines that can make you sleepy or slow your breathing, antidepressants, MAO inhibitors, atropine, benztropine, dimenhydrinate, glycopyrrolate, mepenzolate, methscopolamine, scopolamine, bladder or urinary medications, bronchodilators, or irritable bowel medications. Tell your doctor all medications and supplements you use.

Norco 5/325 During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant while using Norco 5/325. It is unknown if Norco 5/325 is harmful to a fetus, but it could cause breathing problems or addiction/withdrawal symptoms in a newborn. Both medications in Norco 5/325 can pass into breast milk and may harm a nursing baby. Breastfeeding while taking Norco 5/325 is not recommended.

Additional Information

Our Norco 5/325 Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

 

Norco 5-325 Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

Call your doctor at once if you have:

• noisy breathing, sighing, shallow breathing, breathing that stops;
• a light-headed feeling, like you might pass out;
• liver problems--nausea, upper stomach pain, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
• low cortisol levels-- nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness; o
• high levels of serotonin in the body--agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea.

Serious breathing problems may be more likely in older adults and in those who are debilitated or have wasting syndrome or chronic breathing disorders.

Common side effects include:

• dizziness, drowsiness, feeling tired;
• nausea, vomiting, stomach pain;
• constipation; or
• headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Norco 5-325 (Hydrocodone Bitartrate and Acetaminophen)

 

Norco 5-325 Professional Information

SIDE EFFECTS

The most frequently reported adverse reactions are lightheadedness, dizziness, sedation, nausea and vomiting. These effects seem to be more prominent in ambulatory than in nonambulatory patients, and some of these adverse reactions may be alleviated if the patient lies down.

Other Adverse Reactions Include

Central Nervous System: Drowsi ness, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, psychic dependence, mood changes.

Gastrointestinal System: Prolonged administration of NORCO® may produce constipation.

Genitourinary System: Ureteral spasm, spasm of vesical sphincters and urinary retention have been reported with opiates.

Respiratory Depression: Hydrocodone bitartrate may produce dose-related respiratory depression by acting directly on brain stem respiratory centers (see OVERDOSAGE).

Special Senses : Cases of hearing impairment or permanent loss have been reported predominantly in patients with chronic overdose.

Dermatological: Skin rash, pruritus.

The following adverse drug events may be borne in mind as potential effects of acetaminophen: allergic reactions, rash, thrombocytopenia, agranulocytosis. Potential effects of high dosage are listed in the OVERDOSAGE section.

Drug Abuse And Dependence

Controlled Substance

NORCO® is classified as a Schedule III controlled substance.

Abuse and Dependence

Psychic dependence, physical dependence, and tolerance may develop upon repeated administration of narcotics; therefore, this product should be prescribed and administered with caution. However, psychic dependence is unlikely to develop when NORCO® is used for a short time for the treatment of pain.

Physical dependence, the condition in which continued administration of the drug is required to prevent the appearance of a withdrawal syndrome, assumes clinically significant proportions only after several weeks of continued narcotic use, although some mild degree of physical dependence may develop after a few days of narcotic therapy. Tolerance, in which increasingly large doses are required in order to produce the same degree of analgesia, is manifested initially by a shortened duration of analgesic effect, and subsequently by decreases in the intensity of analgesia. The rate of development of tolerance varies among patients.

Read the entire FDA prescribing information for Norco 5-325 (Hydrocodone Bitartrate and Acetaminophen)