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Imcivree Side Effects Center: Detailed Datasheet
Medically reviewed by Min Clinic Staff | Updated: January 2026
- Generic Name: setmelanotide injection, for subcutaneous use
- Brand Name: Imcivree
- Drug Class: How Do Melanocortin Agonists Work?
Imcivree (Setmelanotide Injection, for Subcutaneous Use ) side effects drug center
Imcivree Side Effects Center
What Is Imcivree?
Imcivree (setmelanotide) is a melanocortin 4 (MC4) receptor agonist indicated for chronic weight management in adult and pediatric patients 6 years of age and older with obesity due to proopiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1 (PCSK1), or leptin receptor (LEPR) deficiency confirmed by genetic testing demonstrating variants in POMC, PCSK1, or LEPR genes that are interpreted as pathogenic, likely pathogenic, or of uncertain significance (VUS).
What Are Side Effects of Imcivree?
Side effects of Imcivree include:
- injection site reactions,
- skin hyperpigmentation,
- nausea,
- headache,
- diarrhea,
- abdominal pain,