Navigation

Biorphen

  • Generic Name: phenylephrine hydrochloride injection
  • Brand Name: Biorphen

Biorphen (Phenylephrine Hydrochloride Injection ) side effects drug center

  • Related Drugs
  • Biorphen Side Effects Center

    What Is Biorphen?

    Biorphen (phenylephrine hydrochloride) is an alpha-1 adrenergic receptor agonist used to treat clinically important low blood pressure (hypotension) resulting primarily from vasodilation in the setting of anesthesia.

    What Are Side Effects of Biorphen?

    Side effects of Biorphen include:

    Dosage for Biorphen

    Dosing of Biorphen for treatment of hypotension during anesthesia is given as a bolus intravenous injection of 40 mcg to 100 mcg every 1-2 minutes as needed, not to exceed 200 mcg.

    Biorphen In Children

    Safety and effectiveness of Biorphen in pediatric patients has not been established.

    What Drugs, Substances, or Supplements Interact with Biorphen?

    Biorphen may interact with other medicines such as:

    Tell your doctor all medications and supplements you use.

    Biorphen During Pregnancy and Breastfeeding

    Tell your doctor if you are pregnant or plan to become pregnant before using Biorphen; it is unknown how it would affect a fetus It is unknown if Biorphen passes into breast milk. Consult your doctor before breastfeeding.

    Additional Information

    Our Biorphen (phenylephrine hydrochloride) Injection, for Intravenous Use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

    This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Biorphen Professional Information

    SIDE EFFECTS

    Adverse reactions to BIORPHEN are primarily attributable to excessive pharmacologic activity. Adverse reactions reported in published clinical studies, observational trials, and case reports of BIORPHEN are listed below by body system. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to estimate their frequency reliably or to establish a causal relationship to drug exposure.

    Cardiac disorders: Reflex bradycardia, lowered cardiac output, ischemia, hypertension, arrhythmias

    Gastrointestinal disorders: Epigastric pain, vomiting, nausea

    Nervous system disorders: Headache, blurred vision, neck pain, tremors

    Vascular disorders: Hypertensive crisis

    Respiratory, Thoracic and Mediastinal Disorders: Dyspnea

    Skin and subcutaneous tissue disorders: Pruritis

    DRUG INTERACTIONS

    Interactions That Augment Pressor Effect

    The increasing blood pressure effect of BIORPHEN is increased in patients receiving:

    • Monoamine oxidase inhibitors (MAOI)
    • Oxytocin and oxytocic drugs
    • Tricyclic antidepressants
    • Angiotensin, aldosterone
    • Atropine
    • Steroids, such as hydrocortisone
    • Norepinephrine transporter inhibitors, such as atomoxetine
    • Ergot alkaloids, such as methylergonovine maleate

    Interactions That Antagonize The Pressor Effect

    The increasing blood pressure effect of BIORPHEN is decreased in patients receiving:

    • α-adrenergic antagonists
    • Phosphodiesterase Type 5 inhibitors
    • Mixed α- and β-receptor antagonists
    • Calcium channel blockers, such as nifedipine
    • Benzodiazepines
    • ACE inhibitors
    • Centrally acting sympatholytic agents, such as reserpine, guanfacine

    Read the entire FDA prescribing information for Biorphen (Phenylephrine Hydrochloride Injection )

    © Biorphen Patient Information is supplied by Cerner Multum, Inc. and Biorphen Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.