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Ayvakit Side Effects Center
Medically reviewed by Min Clinic Staff | Updated: January 2026
- Generic Name: avapritinib tablets
- Brand Name: Ayvakit
- Drug Class: Antineoplastic Tyrosine Kinase Inhibitors, PDGFR-alpha Inhibitors
Ayvakit (Avapritinib Tablets) side effects drug center
Ayvakit Side Effects Center
What Is Ayvakit?
Ayvakit (avapritinib) is a kinase inhibitor used to treat adults with unresectable or metastatic gastrointestinal stromal tumor (GIST) harboring a platelet-derived growth factor receptor alpha (PDGFRA) exon 18 mutation, including PDGFRA D842V mutations. Ayvakit is also used to treat adult patients with advanced systemic mastocytosis (AdvSM), which includes patients with aggressive systemic mastocytosis (ASM), systemic mastocytosis with an associated hematological neoplasm (SM-AHN), and mast cell leukemia (MCL).
What Are Side Effects of Ayvakit?
Side effects of Ayvakit include:
- fluid retention (edema),
- nausea,
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