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Aplisol

Aplisol (Tuberculin Purified Protein Derivative) side effects drug center

 

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Aplisol Side Effects Center

What Is Aplisol?

Aplisol (tuberculin purified protein derivative, diluted [stabilized solution]) is a purified protein fraction used as an aid in the detection of infection with Mycobacterium tuberculosis.

What Are Side Effects of Aplisol?

Side effects of Aplisol include:

  • reactions at the test site (pain, itching, discomfort. blisters, ulceration, or tissue death),
  • scarring at the test site (in strong positive test reactions)
  • local hypersensitivity reactions (redness, itching, swelling, hives, and rash), and
  • systemic allergic reactions (including rash, hives, skin swelling, itching, and anaphylaxis)

Dosage for Aplisol

The 0.1 mL dose of Aplisol is equivalent to the 5 tuberculin units (TU) dose of Tuberculin PPD, which is the standard strength used for intradermal Mantoux testing.

Aplisol In Children

Because their immune systems are immature, many neonates and infants under 6 weeks of age, who are infected with

  • M. tuberculosis
  • , may not have a delayed hypersensitivity reaction to a tuberculin test. Older infants and children develop tuberculin sensitivity 3- 6 weeks, and up to 3 months, after initial infection Infants and children who have been exposed to persons with active tuberculosis should be considered positive when reaction to the tuberculin skin test measures >5 mm. Those children younger than 4 years of age who are exposed to persons at increased risk to acquire tuberculosis are considered positive when reaction measures >10 mm. Children with minimal risk exposure to tuberculosis would be considered positive when reaction measures >15 mm.

    What Drugs, Substances, or Supplements Interact with Aplisol?

    Aplisol may interact with other medicines such as: