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Sanvar: Full Drug Profile
Medically reviewed by Min Clinic Staff | Updated: January 2026
Sanvar - General Information
Sanvar is a synthetic octapeptide somatostatin analog. It was being studied for the treatment of cancer.
Pharmacology of Sanvar
Sanvar is a somatostatin analog with a higher metabolic stability than the parent hormone. Sanvar reduces splanchnic blood flow; inhibits growth hormone release, and inhibits the release of peptides and vasoactive compounds from neuroendocrine tumors.
Additional information about Sanvar
- Sanvar Indication
For the treatment of esophageal variceal bleeding in patients with cirrhotic liver disease and has also shown efficacy in the treatment of patients with AIDS-related diarrhea.
- Mechanism Of Action
- The exact mechanism of action is unknown, although one study has provided in vitro and in vivo evidence for a tachykinin NK1 receptor antagonist effect in the analgesic effects of vapreotide (PMID: 7556407).
- Generic Name
- Vapreotide
- Synonyms
- Vapreotide acetate; Vapreotida [INN-Spanish]; Vapreotidum [inn-latin]; RC-160
- Drug Category
- Analgesics; Antineoplastic Agents
- Drug Type
- Small Molecule; Approved; Investigational
- Other Brand Names containing Vapreotide
- Sanvar; Sanvar IR;
- Toxicity (Overdose)
- Safety data are limited, however, headache, fatigue, diarrhea, nausea, vomiting, and abdominal pain have been reported commonly with the use of vapreotide.
- Half Life
- 30 minutes
- Chemical IUPAC Name
- 10-(4-aminobutyl)-N-[1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-19-[(2-amino-3-phenylpropanoyl)amino]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
- Chemical Formula
- C57H70N12O9S2
- Organisms Affected
- Humans and other mammals