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Lisuride Maleate: Full Drug Profile

Medically reviewed by Min Clinic Staff | Updated: January 2026

Lisuride Maleate - General Information

An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists). [PubChem]

 

Pharmacology of Lisuride Maleate

Not Available

 

Additional information about Lisuride Maleate

Lisuride Maleate Indication

For the management of Parkinson's Disease

Mechanism Of Action
Lisuride Maleate is an anti-Parkinson drug chemically related to the dopaminergic ergoline Parkinson's drugs. Lisuride Maleate binds to the 5-HT(1A) and 5-HT(2A/2C) receptors. It is also thought to bind to the dopamine receptor and to act as a dopamine agonist. Evidence has also emerged that Lisuride Maleate also binds to the Histamine H1 receptor. Lisuride Maleate is also used to lower prolactin and, in low doses, to prevent migraine attacks.
Generic Name
Lisuride
Drug Category
Antiparkinson Agents; Antidyskinetics
Drug Type
Small Molecule; Approved
Other Brand Names containing Lisuride
Lisurida [Inn-Spanish]; Lisuride Maleate; Lisuride [Inn]; Lisuridum [Inn-Latin]; Lysuride;
Protein Binding
about 15%
Chemical Formula
C20H26N4O
Organisms Affected
Humans and other mammals