Inhiston: Full Drug Profile

Inhiston - General Information

One of the histamine H1 antagonists with little sedative action. It is used in treatment of hay fever, rhinitis, allergic dermatoses, and pruritus. [PubChem]

Pharmacology of Inhiston

Inhiston is an antihistamine used to treat allergic conditions such as hay fever or urticaria. It is generally sold in combination with other medications, rather than as a stand-alone drug.

Inhiston for patients

1. Products containing antihistamines may cause drowsiness.
2. Patients should not engage in activities requiring mental alertness, such as driving or operating machinery or appliances.
3. Alcohol or other sedative drugs may enhance the drowsiness caused by antihistamines.
4. Patients should not take Pheniramine Tablets if they are receiving a monoamine oxidase inhibitor or within 2 weeks of stopping such treatment.
5. This medication should not be given to children less than 12 years of age.

Inhiston Interactions

Inhiston Contraindications

Antihistamines should not be used to treat lower respiratory tract symptoms, including asthma. This product is contraindicated in patients with narrow-angle glaucoma or urinary retention, and in patients receiving monoamine oxidase (MAO) inhibitor therapy or within 2 weeks of stopping such treatment. It is also contraindicated in patients with severe hypertension, severe coronary artery disease, hyperthyroidism, and in those who have shown hypersensitivity or idiosyncrasy to its components, to adrenergic agents, or to other drugs of similar chemical structures. Manifestations of patient idiosyncrasy to adrenergic agents include: insomnia, dizziness, weakness, tremor, or arrhythmias.

Additional information about Inhiston

Inhiston Indication

Used to treat allergic conditions such as hay fever or urticaria.

Mechanism Of Action

Antihistamines such as pheniramine appear to compete with histamine for histamine H1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of H1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release.

Generic Name

Pheniramine

Synonyms

2-(alpha-(2-Dimethylaminoethyl)benzyl)pyridine; 2-(3-Dimethylamino-1-phenylpropyl)pyridine; 1-Phenyl-1-(2-pyridyl)-3-dimethylaminopropane; 2-[.alpha.-(2-Dimethylaminoethyl)benzyl]pyridine; 2-[.alpha.-[2-(Dimethylamino)ethyl]benzyl]pyridine; Dimethyl(3-phenyl-3-(2-pyridyl)propyl)amine; Feniramina [inn-spanish]; Feniramine; Pheniraminum [inn-latin]; Propheniramine; Prophenpyridamine

Drug Category

Anti-Allergic Agents; Antipruritic Agents; Histamine H1 Antagonists

Drug Type

Small Molecule; Approved

Other Brand Names containing Pheniramine

AVIL; Inhiston; Metron; Pyriton; Trimeton; Tripoton;

Biotransformation

Hepatic hydroxylation, demethylation and glucuronidation.

Dosage Forms of Inhiston

Powder Oral

Chemical IUPAC Name

N,N-dimethyl-3-phenyl-3-pyridin-2-ylpropan-1-amine

Chemical Formula

C16H20N2

Pheniramine on Wikipedia

https://en.wikipedia.org/wiki/Pheniramine

Organisms Affected

Humans and other mammals