Reglan Injection
- Generic Name: metoclopramide injection
- Brand Name: Reglan Injection
Reglan Injection (Metoclopramide Injection) side effects drug center
- Related Drugs
- restlessness,
- drowsiness,
- fatigue,
- trouble sleeping (insomnia),
- headache,
- confusion,
- dizziness,
- skin flushing,
- breast swelling or tenderness,
- nipple discharge,
- dry mouth,
- nausea,
- vomiting,
- diarrhea,
- constipation,
- skin rash or itching, or
- injection site reactions (pain, itching, burning, swelling or a lump)
- tremors or shaking in your arms or legs;
- uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); or
- any new or unusual muscle movements you cannot control.
- confusion, depression, thoughts of suicide or hurting yourself;
- slow or jerky muscle movements, problems with balance or walking;
- mask-like appearance in your face;
- a seizure;
- anxiety, agitation, jittery feeling, trouble staying still, trouble sleeping;
- swelling, feeling short of breath, rapid weight gain; or
- severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.
- feeling restless;
- feeling drowsy or tired;
- lack of energy;
- nausea, vomiting;
- headache, confusion; or
- sleep problems (insomnia).
Reglan Injection (metoclopramide) is a prokinetic drug used for the relief of symptoms associated with acute and recurrent diabetic gastric stasis, to prevent nausea and vomiting from chemotherapy, to prevent postoperative nausea and vomiting, to facilitate small bowel intubation, and to stimulate gastric emptying. Reglan Injection is available in generic form. Common side effects of Reglan Injection include:
Dose of Reglan Injection depends on the condition being treated. Reglan Injection may interact with anticholinergic drugs, narcotics, alcohol, sedatives, hypnotics, tranquilizers, monoamine oxidase inhibitors (MAOIs), digoxin, acetaminophen, tetracycline, levodopa, ethanol, or cyclosporine. Tell your doctor all medications and supplements you use. During pregnancy, Reglan Injection should be used only if prescribed. This drug passes into breast milk. Consult your doctor before breastfeeding.
Our Reglan Injection (metoclopramide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop taking metoclopramide and call your doctor at once if you have any of these SIGNS OF A SERIOUS MOVEMENT DISORDER, which may occur within the first 2 days of treatment:
Call your doctor at once if you have:
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Reglan Injection (Metoclopramide Injection)
SIDE EFFECTS
In general, the incidence of adverse reactions correlates with the dose and duration of metoclopramide administration. The following reactions have been reported, although in most instances, data do not permit an estimate of frequency:
CNS Effects
Restlessness, drowsiness, fatigue, and lassitude may occur in patients receiving the recommended prescribed dosage of REGLAN Injection (metoclopramide injection) . Insomnia, headache, confusion, dizziness, or mental depression with suicidal ideation also may occur (see WARNINGS). In cancer chemotherapy patients being treated with 1-2 mg/kg per dose, incidence of drowsiness is about 70%. There are isolated reports of convulsive seizures without clear-cut relationship to metoclopramide. Rarely, hallucinations have been reported.
Extrapyramidal Reactions (EPS)
Acute dystonic reactions, the most common type of EPS associated with metoclopramide, occur in approximately 0.2% of patients (1 in 500) treated with 30 to 40 mg of metoclopramide per day. In cancer chemotherapy patients receiving 1-2 mg/kg per dose, the incidence is 2% in patients over the ages of 30-35, and 25% or higher in pediatric patients and adult patients less than 30 years of age who have not had prophylactic administration of diphenhydramine. Symptoms include involuntary movements of limbs, facial grimacing, torticollis, oculogyric crisis, rhythmic protrusion of tongue, bulbar type of speech, trismus, opisthotonus (tetanus-like reactions), and, rarely, stridor and dyspnea possibly due to laryngospasm; ordinarily these symptoms are readily reversed by diphenhydramine (see WARNINGS).
Parkinsonian-like symptoms may include bradykinesia, tremor, cogwheel rigidity, mask-like facies (see WARNINGS).
Tardive dyskinesia most frequently is characterized by involuntary movements of the tongue, face, mouth, or jaw, and sometimes by involuntary movements of the trunk and/or extremities; movements may be choreoathetotic in appearance (see WARNINGS).
Motor restlessness (akathisia) may consist of feelings of anxiety, agitation, jitteriness, and insomnia, as well as inability to sit still, pacing, foot tapping. These symptoms may disappear spontaneously or respond to a reduction in dosage.
Neuroleptic Malignant Syndrome
Rare occurrences of neuroleptic malignant syndrome (NMS) have been reported. This potentially fatal syndrome is comprised of the symptom complex of hyperthermia, muscular rigidity, altered consciousness, and autonomic instability (see WARNINGS).
Endocrine Disturbances
Galactorrhea, amenorrhea, gynecomastia, impotence secondary to hyperprolactinemia (see PRECAUTIONS). Fluid retention secondary to transient elevation of aldosterone (see CLINICAL PHARMACOLOGY).
Cardiovascular
Hypotension, hypertension, supraventricular tachycardia, bradycardia, fluid retention, acute congestive heart failure and possible atrioventricular (AV) block (see CONTRAINDICATIONS and PRECAUTIONS).
Gastrointestinal
Nausea and bowel disturbances, primarily diarrhea.
Hepatic
Rarely, cases of hepatotoxicity, characterized by such findings as jaundice and altered liver function tests, when metoclopramide was administered with other drugs with known hepatotoxic potential.
Renal
Urinary frequency and incontinence.
Hematologic
A few cases of neutropenia, leukopenia, or agranulocytosis, generally without clear-cut relationship to metoclopramide. Methemoglobinemia in adults and especially with overdosage in neonates (see OVERDOSAGE). Sulfhemoglobinemia in adults.
Allergic Reactions
A few cases of rash, urticaria, or bronchospasm, especially in patients with a history of asthma. Rarely, angioneurotic edema, including glossal or laryngeal edema.
Miscellaneous
Visual disturbances. Porphyria.
Transient flushing of the face and upper body, without alterations in vital signs, following high doses intravenously.
Read the entire FDA prescribing information for Reglan Injection (Metoclopramide Injection)
© Reglan Injection Patient Information is supplied by Cerner Multum, Inc. and Reglan Injection Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.