Gloperba
- Generic Name: colchicine oral solution
- Brand Name: Gloperba
- Drug Class: Antigout Agents
Gloperba (Colchicine Oral Solution) side effects drug center
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- gastrointestinal symptoms,
- including diarrhea,
- nausea,
- vomiting, and
- abdominal pain
What Is Gloperba?
Gloperba (colchicine) Oral Solution is an anti-gout agent indicated for prevention of gout flares in adults.
What Are Side Effects of Gloperba?
Common side effects of Gloperba include:
Dosage for Gloperba
The dose of Gloperba is 0.6 mg (5 mL) once or twice daily.
What Drugs, Substances, or Supplements Interact with Gloperba?
Gloperba may interact with grapefruit juice, erythromycin, verapamil, cyclosporine, clarithromycin, ketoconazole, HMG-CoA reductase inhibitors (statins), and fibrates. Tell your doctor all medications and supplements you use.
Gloperba During Pregnancy or Breastfeeding
Tell your doctor if you are pregnant or plan to become pregnant before using Gloperba; it is not expected to harm a fetus at normal doses. Gloperba may very rarely cause infertility in males. Gloperba passes into breast milk. Consult your doctor before breastfeeding.
Additional Information
Our Gloperba (colchicine) Oral Solution Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
SIDE EFFECTS
Gastrointestinal disorders are the most common adverse reactions with colchicine. These disorders are often the first signs of toxicity and may indicate that the colchicine dose needs to be reduced or therapy stopped. These disorders include diarrhea, nausea, vomiting, and abdominal pain.
Colchicine has been reported to cause neuromuscular toxicity, which may present as muscle pain or weakness [see WARNINGS AND PRECAUTIONS].
Toxic manifestations associated with colchicine include myelosuppression, disseminated intravascular coagulation and injury to cells in the renal, hepatic, circulatory and central nervous systems. These toxicities most often occur with excessive accumulation or overdosage [see OVERDOSAGE].
The following adverse reactions have been reported with colchicine. These adverse reactions have been generally reversible upon interrupting treatment or lowering the dose of colchicine.
Neurological: sensory motor neuropathy
Dermatological: alopecia, maculopapular rash, purpura, rash
Digestive: abdominal cramping, abdominal pain, diarrhea, lactose intolerance, nausea, vomiting
Hematological: leukopenia, granulocytopenia, thrombocytopenia, pancytopenia, aplastic anemia
Hepatobiliary: elevated AST, elevated ALT
Musculoskeletal: myopathy, elevated CPK, myotonia, muscle weakness, muscle pain, rhabdomyolysis
Reproductive: azoospermia, oligospermia
Read the entire FDA prescribing information for Gloperba (Colchicine Oral Solution)
© Gloperba Patient Information is supplied by Cerner Multum, Inc. and Gloperba Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.